Evolution of novel wood decay mechanisms in Agaricales revealed by the genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.
Evolution of novel wood decay mechanisms in Agaricales revealed by the genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.
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DOI：
10.1016/j.fgb.2015.02.002
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发表时间：
2015-03
影响因子：
3
通讯作者：
Hibbett, David S.
中科院分区：
文献类型：
--
作者：
Floudas, Dimitrios;Held, Benjamin W.;Riley, Robert;Nagy, Laszlo G.;Koehler, Gage;Ransdell, Anthony S.;Younus, Hina;Chow, Julianna;Chiniquy, Jennifer;Lipzen, Anna;Tritt, Andrew;Sun, Hui;Haridas, Sajeet;LaButti, Kurt;Ohm, Robin A.;Kuees, Ursula;Blanchette, Robert A.;Grigoriev, Igor V.;Minto, Robert E.;Hibbett, David S.
伞形孢菌亚门的木材腐烂机制传统上分为两类，称为白腐病和褐腐病。最近，这种二分法的准确性受到质疑。在这里，我们结合比较基因组学和木材腐烂实验，展示了伞菌目白腐真菌 Cylindrobasidium torrendii 和褐腐真菌 Fistulina hepatica 的基因组序列。 Cylindrobasidium torrendii 与白腐病根病原体蜜环菌密切相关，而 F. hepatica 与裂褶菌有关，据报道后者会引起白腐病。我们的结果表明，C. torrendii 和 S. commune 介于白腐真菌和褐腐真菌之间，但同时它们表现出类似于软腐病的腐烂特征。这两种物种都会导致木材微弱腐烂并降解所有木材成分，但使中间层保持完整。它们与木质素降解相关的基因含量减少，类似于褐腐真菌，但两者都保留了丰富的与碳水化合物降解相关的基因，类似于白腐真菌。这些特征似乎是从具有更强木质素分解能力的白腐祖先进化而来的。肝瘘管在其基因组中发现的木材腐烂基因及其引起的腐烂方面都显示出褐腐病的特征。然而，与纤维素降解相关的基因仍然存在，这是与其白腐祖先共有的拟形特征。四种与木材降解相关的基因（其同源物在褐腐真菌中经常丢失）在肝镰刀菌基因组中显示出假基因化的迹象。这些结果表明，肝镰刀菌向褐腐病生活方式的转变可能是一个持续的过程。我们的结果强化了这样的观点，即木材腐烂机制比最初想象的更加多样化，并且应该重新审视伞菌亚门中木材腐烂机制分为白腐病和褐腐病的二分法。
Wood decay mechanisms in Agaricomycotina have been traditionally separated in two categories termed white and brown rot. Recently the accuracy of such a dichotomy has been questioned. Here, we present the genome sequences of the white rot fungus Cylindrobasidium torrendii and the brown rot fungus Fistulina hepatica both members of Agaricales, combining comparative genomics and wood decay experiments. Cylindrobasidium torrendii is closely related to the white-rot root pathogen Armillaria mellea, while F. hepatica is related to Schizophyllum commune, which has been reported to cause white rot. Our results suggest that C. torrendii and S. commune are intermediate between white-rot and brown-rot fungi, but at the same time they show characteristics of decay that resembles soft rot. Both species cause weak wood decay and degrade all wood components but leave the middle lamella intact. Their gene content related to lignin degradation is reduced, similar to brown-rot fungi, but both have maintained a rich array of genes related to carbohydrate degradation, similar to white-rot fungi. These characteristics appear to have evolved from white-rot ancestors with stronger ligninolytic ability. Fistulina hepatica shows characteristics of brown rot both in terms of wood decay genes found in its genome and the decay that it causes. However, genes related to cellulose degradation are still present, which is a plesiomorphic characteristic shared with its white-rot ancestors. Four wood degradation-related genes, homologs of which are frequently lost in brown-rot fungi, show signs of pseudogenization in the genome of F. hepatica. These results suggest that transition towards a brown rot lifestyle could be an ongoing process in F. hepatica. Our results reinforce the idea that wood decay mechanisms are more diverse than initially thought and that the dichotomous separation of wood decay mechanisms in Agaricomycotina into white rot and brown rot should be revisited.
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影响因子：
4.4
作者：
Collins, Cassandra;Keane, Thomas M.;Turner, Daniel J.;O'Keeffe, Grainne;Fitzpatrick, David A.;Doyle, Sean
通讯作者：
Doyle, Sean
DOI：
10.1139/b88-251
发表时间：
1988-09-01
期刊：
CANADIAN JOURNAL OF BOTANY-REVUE CANADIENNE DE BOTANIQUE
影响因子：
--
作者：
BLANCHETTE, RA;OBST, JR;WELIKY, K
通讯作者：
WELIKY, K
影响因子：
10.7
作者：
Castresana, J
通讯作者：
Castresana, J
影响因子：
4.1
作者：
Crepin, VF;Faulds, CB;Connerton, IF
通讯作者：
Connerton, IF
影响因子：
7
作者：
Birney, E;Durbin, R
通讯作者：
Durbin, R