Open and closed 5 S ribosomal RNA, the only two universal structures encoded in the nucleotide sequences.
Open and closed 5 S ribosomal RNA, the only two universal structures encoded in the nucleotide sequences.
复制标题
开放和闭合 5S 核糖体 RNA,这是核苷酸序列中编码的唯一两种通用结构。
DOI:
10.1016/s0022-2836(83)80172-7
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发表时间:
1983
影响因子:
5.6
通讯作者:
G. Bolshoi
中科院分区:
文献类型:
--
作者:
Edward N. Trifonov;G. Bolshoi
The nucleotide sequences of small ribosomal RNA (5 S rRNA) molecules of different organisms are presumably designed to ensure folding of these molecules in some standard secondary structure(s). To extract this message contained in the sequences we have plotted the triangular matrix diagrams of all potential hairpins for 44 representative 5 S rRNA sequences. Subjecting these diagrams to simple image-processing procedures we have found that only five hairpins are universally present in all known 5 S rRNA molecules. Two of these hairpins share the same stretch of the nucleotide sequence, others being independent. Thus, only two major secondary structures of 5 S rRNA can be formed. These are of the well-known Y-like (open) form and a novel P-like form closed by the tertiary interaction which involves two complementary stretches four to seven bases long.
影响因子:
14.9
作者:
G. Studnicka;F. Eiserling;J. Lake
通讯作者:
G. Studnicka;F. Eiserling;J. Lake
影响因子:
5.6
作者:
Farber,NM;Cantor,CR
通讯作者:
Cantor,CR
影响因子:
14.9
作者:
Kime,MJ;Moore,PB
通讯作者:
Moore,PB