Open and closed 5 S ribosomal RNA, the only two universal structures encoded in the nucleotide sequences.

Open and closed 5 S ribosomal RNA, the only two universal structures encoded in the nucleotide sequences.
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开放和闭合 5S 核糖体 RNA,这是核苷酸序列中编码的唯一两种通用结构。

DOI:
10.1016/s0022-2836(83)80172-7
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发表时间:
1983
影响因子:
5.6
通讯作者:
G. Bolshoi
G. Bolshoi
中科院分区:
生物学2区
文献类型:
--
作者:
Edward N. Trifonov;G. Bolshoi

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不同生物体的小核糖体RNA(5S rRNA)分子的核苷酸序列可能被设计为确保这些分子以某些标准二级结构折叠。为了提取序列中包含的信息,我们绘制了44个代表性5 S rRNA序列的所有潜在发夹的三角矩阵图。将这些图进行简单的图像处理程序,我们发现只有五个发夹普遍存在于所有已知的5 S rRNA分子中。这些发夹中的两个共享相同的核苷酸序列,其他的是独立的。因此,只有两个主要的二级结构的5 S rRNA可以形成。这些都是众所周知的Y-样(开放)的形式和一个新的P-样的形式关闭三级相互作用,其中涉及两个互补的延伸4至7个碱基长。
The nucleotide sequences of small ribosomal RNA (5 S rRNA) molecules of different organisms are presumably designed to ensure folding of these molecules in some standard secondary structure(s). To extract this message contained in the sequences we have plotted the triangular matrix diagrams of all potential hairpins for 44 representative 5 S rRNA sequences. Subjecting these diagrams to simple image-processing procedures we have found that only five hairpins are universally present in all known 5 S rRNA molecules. Two of these hairpins share the same stretch of the nucleotide sequence, others being independent. Thus, only two major secondary structures of 5 S rRNA can be formed. These are of the well-known Y-like (open) form and a novel P-like form closed by the tertiary interaction which involves two complementary stretches four to seven bases long.
DOI: 10.1093/nar/9.8.1885
发表时间: 1981-04
影响因子: 14.9
作者:
G. Studnicka;F. Eiserling;J. Lake
通讯作者: G. Studnicka;F. Eiserling;J. Lake
大肠杆菌 5S 核糖体 RNA 溶液结构的缓慢氚交换研究。
DOI: 10.1016/0022-2836(81)90433-2
发表时间: 1981
影响因子: 5.6
作者:
Farber,NM;Cantor,CR
通讯作者: Cantor,CR
NMR 证据证明 5S RNA 存在两种天然构象。
DOI: 10.1093/nar/10.16.4973
发表时间: 1982
影响因子: 14.9
作者:
Kime,MJ;Moore,PB
通讯作者: Moore,PB