Vascularized composite allotransplantation: a closer look at the banff working classification
Vascularized composite allotransplantation: a closer look at the banff working classification
复制标题
血管化复合同种异体移植：仔细观察班夫工作分类
作者：
Michelle Schneider;A. Cardones;M. Selim;L. Cendales
第一次班夫血管化复合同种异体移植会议于2007年举行，以标准化排斥反应严重程度和类型的表征和报告标准。因此，2007年Banff VCA皮肤移植病理学工作分类正式形成，现在作为VCA排斥反应诊断的标准。与其他工作分类系统类似，已确定了优势和局限性，包括标本的充分性、等级之间严重程度的定义、再现性、标本的充分性、拒绝的类型以及分子和基因组方法等新技术的整合。尽管迄今为止进行和随访的病例数量相对较少，但基于VCA领域积累的经验以及与其他实体器官的相似性，正在报告和表征其他表型，如抗体介导的排斥反应、纤维化、萎缩和血管变化。本研究的目的是考虑班夫VCA工作系统的优势和局限性，并强调在这一新兴的移植领域与组织病理学相关的持续挑战和机遇。
The first Banff vascularized composite allotransplantation meeting was held in 2007 to standardize criteria for the characterization and reporting of severity and types of rejection. As a result, the 2007 Banff VCA working classification for skin allograft pathology was formalized and now serves as the standard for diagnosis of VCA rejection. Similar to other working classification systems, strengths and limitations have been identified including the adequacy of the specimen, the definition of severity between grades, the reproducibility, the adequacy of the specimens, the types of rejection, and the integration of newer technologies such as molecular and genomic approaches. Although a relatively few number of cases have been performed and followed up to date, additional phenotypes such as antibody‐mediated rejection, fibrosis, atrophy, and vascular changes are being reported and characterized based on accumulated experience in the field of VCA and parallels with other solid organs. This study aims to consider strengths and limitations of the Banff VCA working system and highlights ongoing challenges and opportunities available related to histopathology in this emerging field of transplantation.
影响因子：
1.9
作者：
Baran U;Li Y;Wang RK
通讯作者：
Wang RK
影响因子：
2.5
作者：
Sadowski, Elizabeth A.;Djamali, Arjang;Wentland, Andrew L.;Muehrer, Rebecca;Becker, Bryan N.;Grist, Thomas M.;Fain, Sean B.
通讯作者：
Fain, Sean B.