Systemic and intracerebroventricular injections of vasotocin inhibit appetitive and consummatory components of male sexual behavior in Japanese quail.

Systemic and intracerebroventricular injections of vasotocin inhibit appetitive and consummatory components of male sexual behavior in Japanese quail.
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全身和脑室内注射血管催产素可抑制日本鹌鹑雄性性行为的食欲和完成成分。

DOI:
10.1037//0735-7044.112.1.233
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发表时间:
1998
影响因子:
1.9
通讯作者:
Balthazart,J
Balthazart,J
中科院分区:
医学4区
文献类型:
--
作者:
Castagna,C;Absil,P;Foidart,A;Balthazart,J

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作者调查了经去势睾酮治疗的雄性日本鹌鹑中催产素 (VT) 的行为作用。注射 VT 以剂量依赖性方式抑制性行为的食欲和完成成分以及乌鸦的发生频率。作者在注射 V1 受体拮抗剂 dPTyr (Me) AVP 后观察到相反的效果。中枢注射后较低剂量的 VT 比全身注射后更活跃,并且 VT 全身注射的作用被中枢注射 dPTyr (Me) AVP 阻断。行为抑制与全身注射后的改良利尿有关,但与中枢注射无关。这些结果提供了直接证据,表明 VT 通过对大脑的直接作用(独立于其外周利尿作用)来影响鹌鹑的雄性性行为。
The authors investigated the behavioral actions of vasotocin (VT) in castrated testosterone-treated male Japanese quail. The appetitive and consummatory components of sexual behavior as well as the occurrence frequency of crows were inhibited, in a dose-dependent manner, by injections of VT. The authors observed opposite effects after injection of the V1 receptor antagonist, dPTyr (Me) AVP. Lower doses of VT were more active after central than after systemic injection, and effects of systemic injections of VT were blocked by a central injection of dPTyr (Me) AVP. The behavioral inhibition was associated with a modified diuresis after systemic but not central injection. These results provide direct evidence that VT affects male sexual behavior in quail by a direct action on the brain independent of its peripheral action on diuresis.
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