Ischemic Stroke in a SARS-CoV-2-Positive Octagenarian Without Cardiovascular Risk Factors: A Case Report.
Ischemic Stroke in a SARS-CoV-2-Positive Octagenarian Without Cardiovascular Risk Factors: A Case Report.
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DOI：
10.7759/cureus.23654
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发表时间：
2022-03
影响因子：
1.2
通讯作者：
Finsterer, Josef
中科院分区：
文献类型：
--
作者：
Finsterer, Josef
缺血性和出血性中风越来越被认为是严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染的并发症。在SARS-CoV-2感染的中风患者中没有心血管危险因素支持因果关系，如以下报告所示。患者是一名86岁女性，在轻度SARS-CoV-2感染期间出现轻度、肱面、右侧偏侧症状。脑磁共振成像（MRI）显示左心室周围白色物质中存在相应的小的亚急性缺血性病变，左丘脑中存在微出血。在双重血小板聚集抑制剂治疗下，神经功能缺损在三周内几乎完全消退。如果认为经典的心血管危险因素缺失，SARS-CoV-2感染和中风之间的因果关系就很可能存在。由病毒或针对病毒的免疫反应引起的血管病、凝血病和心脏病可作为脑病变的病理生理学解释。结论：SARS-CoV-2感染可导致缺血性脑卒中的发生，支持SARS-CoV-2感染与缺血性脑卒中因果关系的观点多于反对。
Ischemic and hemorrhagic strokes are increasingly recognized as complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. The absence of cardiovascular risk factors in SARS-CoV-2-infected patients who suffer a stroke supports a causal relationship as shown in the following report. The patient is an 86-year-old female who developed a mild, brachio-facial, right-sided hemi-symptomatic during a mild infection with SARS-CoV-2. Cerebral magnetic resonance imaging (MRI) showed a corresponding, small, subacute, ischemic lesion in the left periventricular white matter and a microbleed in the left thalamus. Under dual platelet aggregation inhibitor therapy, the neurological deficits regressed almost completely within three weeks. If one considers that classic cardiovascular risk factors were missing, a causal link between the SARS-CoV-2 infection and the stroke becomes likely. Vasculopathy, coagulopathy, and cardiac disease caused by the virus or the immune response against it serve as pathophysiological explanations for the cerebral lesions. It is concluded that ischemic stroke can occur during infection with SARS-CoV-2. There are more arguments for than against a causal relationship between the viral infection and ischemic stroke.
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影响因子：
13.8
作者：
Li P;Zhao W;Kaatz S;Latack K;Schultz L;Poisson L
通讯作者：
Poisson L
DOI：
10.1016/j.clinsp.2022.100012
发表时间：
2022
期刊：
Clinics (Sao Paulo, Brazil)
影响因子：
--
作者：
Finsterer J;Scorza FA;Scorza CA;Fiorini AC
通讯作者：
Fiorini AC
DOI：
10.3390/life12020207
发表时间：
2022-01-29
期刊：
Life (Basel, Switzerland)
影响因子：
--
作者：
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通讯作者：
Desai M
影响因子：
3.8
作者：
Chang J;Bulwa Z;Breit H;Cherian LJ;Conners JJ;Song SY;Dafer RM
通讯作者：
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