Nutraceuticals for the Treatment of IBD: Current Progress and Future Directions.
Nutraceuticals for the Treatment of IBD: Current Progress and Future Directions.
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治疗 IBD 的营养药物：当前进展和未来方向
DOI：
10.3389/fnut.2022.794169
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发表时间：
2022
影响因子：
5
通讯作者：
He, Wei-Qi
中科院分区：
文献类型：
--
作者：
Ban, Quan-Yao;Liu, Mei;Ding, Ning;Chen, Ying;Lin, Qiong;Zha, Juan-Min;He, Wei-Qi
关键词：
炎症性肠病（IBD）是一种慢性复发缓解型胃肠道炎症性疾病。患者通常在青春期和成年早期被诊断，需要终身治疗。近年来研究发现，饮食在IBD的发病中起着重要作用。饮食可以改变肠道屏障功能，影响肠道植物群的结构和功能，促使免疫紊乱，从而促进炎症。许多患者认为饮食在疾病的发病和治疗中起作用，并自发改变饮食。本文综述了营养保健品如何调节肠道免疫稳态和改善肠道屏障功能。本文综述了膳食纤维、多酚类物质、生物活性肽等营养保健品在IBD防治中的研究成果，为IBD患者寻求更好的替代或补充治疗方法。
Inflammatory bowel disease (IBD) is a chronic relapsing-remitting inflammatory disease of the gastrointestinal tract. Patients are usually diagnosed in adolescence and early adulthood and need lifelong treatment. In recent years, it has been found that diet plays an important role in the pathogenesis of IBD. Diet can change intestinal barrier function, affect the structure and function of intestinal flora, and promote immune disorder, thus promoting inflammation. Many patients believe that diet plays a role in the onset and treatment of the disease and changes their diet spontaneously. This review provides some insights into how nutraceuticals regulate intestinal immune homeostasis and improve intestinal barrier function. We reviewed the research results of dietary fiber, polyphenols, bioactive peptides, and other nutraceuticals in the prevention and treatment of IBD and sought better alternative or supplementary treatment methods for IBD patients.
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影响因子：
64.8
作者：
Chassaing B;Koren O;Goodrich JK;Poole AC;Srinivasan S;Ley RE;Gewirtz AT
通讯作者：
Gewirtz AT
冻干草莓的随机II期试验对食管发育不良癌性病变的患者。
DOI：
10.1158/1940-6207.capr-11-0469
发表时间：
2012-01
期刊：
Cancer prevention research (Philadelphia, Pa.)
影响因子：
--
作者：
Chen T;Yan F;Qian J;Guo M;Zhang H;Tang X;Chen F;Stoner GD;Wang X
通讯作者：
Wang X
影响因子：
6.8
作者：
Almradi, Ahmed;Hanzel, Jurij;Jairath, Vipul
通讯作者：
Jairath, Vipul
影响因子：
3.6
作者：
Avila-Roman, Javier;Talero, Elena;Motilva, Virginia
通讯作者：
Motilva, Virginia
影响因子：
12.8
作者：
Chelakkot C;Ghim J;Ryu SH
通讯作者：
Ryu SH