Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites.
Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites.
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DOI：
10.1016/j.jalz.2009.04.1234
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发表时间：
2009-11
期刊：
影响因子：
--
通讯作者：
Steffens DC
中科院分区：
文献类型：
--
作者：
Potter GG;Plassman BL;Burke JR;Kabeto MU;Langa KM;Llewellyn DJ;Rogers MA;Steffens DC
认知障碍和痴呆症的诊断必须反映美国人口日益多元化和老龄化的情况。这项研究比较了非裔美国人和白人之间的认知障碍和痴呆症的临床诊断的直接测试和线人报告。老龄化，人口统计学和记忆研究的参与者完成了亲自痴呆症评估，并被分配了正常的临床诊断（由痴呆症专家共识小组）;认知障碍，非痴呆症（CIND）;和痴呆症。使用阿尔茨海默病登记协会（CERAD）总分和老年人认知能力下降知情人问卷（IQCODE）来评估认知表现和报告的认知能力下降。较高的CERAD总分与CIND和痴呆的较低几率相关，非洲裔美国人和白人之间的比例相当。在非裔美国人和白人中，较高的IQCODE评分与痴呆症的几率增加有关。较高的IQCODE分数与白人中CIND的几率增加有关，但在非洲裔美国人中则不然。文化差异可能会影响告密者报告的流行CIND和痴呆症。我们的研究结果还强调了需要更多的比较研究，以建立用于诊断这些条件的措施的文化有效性。
The diagnosis of cognitive impairment and dementia must reflect an increasingly diverse and aging United States population. This study compared direct testing and informant reports of cognition with clinical diagnoses of cognitive impairment and dementia between African Americans and whites. Participants in the Aging, Demographics, and Memory Study completed in-person dementia evaluations, and were assigned clinical diagnoses (by a consensus panel of dementia experts) of normal; cognitive impairment, not demented (CIND); and dementia. The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) total score and the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) were used to assess cognitive performance and reported cognitive decline. A higher CERAD total score was associated with lower odds of CIND and dementia, at comparable ratios between African Americans and whites. Higher IQCODE scores were associated with increased odds of dementia in both African Americans and whites. Higher IQCODE scores were associated with increased odds of CIND among whites, but not among African Americans. Cultural differences may influence informant reports of prevalent CIND and dementia. Our findings also highlight the need for more comparative research to establish the cultural validity of measures used to diagnose these conditions.
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影响因子：
9.9
作者：
Manly, JJ;Jacobs, DM;Stern, Y
通讯作者：
Stern, Y
影响因子：
5.7
作者：
Langa, KM;Plassman, BL;Willis, RJ
通讯作者：
Willis, RJ
DOI：
10.1093/geronb/50b.6.s374
发表时间：
1995-11-01
影响因子：
6.2
作者：
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通讯作者：
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影响因子：
6.9
作者：
JORM, AF
通讯作者：
JORM, AF
影响因子：
2.8
作者：
Farran, CJ;Miller, BH;Davis, L
通讯作者：
Davis, L