Assessment of the functional efficacy of root canal treatment with high-frequency waves in rats.
Assessment of the functional efficacy of root canal treatment with high-frequency waves in rats.
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DOI：
10.1371/journal.pone.0239660
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发表时间：
2020
期刊：
影响因子：
3.7
通讯作者：
Hayashi M
中科院分区：
文献类型：
--
作者：
Matsui S;Yoneda N;Maezono H;Kuremoto K;Ishimoto T;Nakano T;Yumoto H;Ebisu S;Noiri Y;Hayashi M
本研究旨在建立大鼠高频波根管治疗模型，探讨高频波对根管治疗的影响，为根尖周炎的治疗提供新的策略。对10周龄雄性Wistar大鼠的下颌第一磨牙进行高频波照射和非高频波照射的根管治疗。对近中牙根进行了放射学、细菌学和免疫化学评价。在根管治疗后3周，照射组的病变体积比非照射组明显减少，表明高频治疗模型的成功开发。根管治疗后使用高频波没有提供额外的杀菌效果。然而，发现高频波照射通过增加成纤维细胞生长因子2和转化生长因子-β1的表达促进宿主侧根尖周病变的愈合，因此可用作根尖周炎的辅助非手术治疗。
The purpose of this study was to develop a high-frequency wave therapy model in rats and to investigate the influence of high-frequency waves on root canal treatment, which may provide a novel strategy for treating apical periodontitis. Root canal treatments with and without high-frequency wave irradiation were performed on the mandibular first molars of 10-week-old male Wistar rats. The mesial roots were evaluated radiologically, bacteriologically, and immunohistochemically. At 3 weeks after root canal treatment, lesion volume had decreased significantly more in the irradiated group than in the non-irradiated group, indicating successful development of the high-frequency therapy model. The use of high-frequency waves provided no additional bactericidal effect after root canal treatment. However, high-frequency wave irradiation was found to promote healing of periapical lesions on the host side through increased expression of fibroblast growth factor 2 and transforming growth factor-β1 and could therefore be useful as an adjuvant nonsurgical treatment for apical periodontitis.
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影响因子：
--
作者：
Pinheiro SL;Silva CCD;Silva LAD;Cicotti MP;Bueno CEDS;Fontana CE;Pagrion LR;Dalmora NP;Daque TT;Campos FU
通讯作者：
Campos FU
DOI：
10.4103/0974-7788.59946
发表时间：
2010-01
期刊：
International journal of Ayurveda research
影响因子：
--
作者：
Kadam P;Bhalerao S
通讯作者：
Bhalerao S
影响因子：
7.6
作者：
Kawahara, T;Murakami, S;Ebisu, S
通讯作者：
Ebisu, S
影响因子：
4.2
作者：
WALKER, RT
通讯作者：
WALKER, RT
影响因子：
3.4
作者：
de Figueiredo, Fabricio Eneas Diniz;Lima, Laila F.;Faria-e-Silva, Andre L.
通讯作者：
Faria-e-Silva, Andre L.