Cortical networks for ethologically relevant behaviors in primates.
Cortical networks for ethologically relevant behaviors in primates.
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DOI：
10.1002/ajp.22065
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发表时间：
2013-05
影响因子：
2.4
通讯作者：
Stepniewska, Iwona
中科院分区：
文献类型：
--
作者：
Kaas, Jon H.;Gharbawie, Omar A.;Stepniewska, Iwona
灵长类大脑中的顶叶-额叶网络是协调行动的核心。生理学和解剖学研究表明，顶叶-额叶网络在灵长类进化的几个分支中是一致组织的，包括原猿类、新世界猫头鹰和松鼠猴以及旧世界猕猴。通过微电极传递的0.5秒脉冲序列的电刺激引起后顶叶皮层（PPC）和额叶运动皮层（FMC）的行为学相关的行动。达到，抓住，防御，和其他复杂的运动模式引起的领域，在FMC和PPC的特征组织。虽然PPC域（例如，到达）可以与其他PPC域（例如，抓取和防御）连接，但其与FMC的连接优先于匹配域（到达）。类似地，PPC域的电刺激和FMC的并行光学成像显示与PPC和FMC域的优先连接性一致的激活模式。灵长类辐射的三个主要分支的成员的PPC和FMC的互连功能域的类似安排的证据表明，顶叶-额叶网络出现在灵长类动物的进化早期。在灵长类动物的近亲，包括兔形目动物，啮齿类动物和树鼩，PPC的小尺寸，表明在古老的灵长类动物出现之前，PPC在运动行为中的参与有限。然而，功能域可能已经在运动皮层的出现之前，古老的灵长类动物。
Parietal–frontal networks in primate brains are central to mediating actions. Physiological and anatomical investigations have shown that the parietal–frontal network is consistently organized across several branches of primate evolution that include prosimian galagos, New World owl and squirrel monkeys, and Old World macaque monkeys. Electrical stimulation with 0.5-sec trains of pulses delivered via microelectrodes evoked ethologically relevant actions from both posterior parietal cortex (PPC) and frontal motor cortex (FMC). Reaching, grasping, defensive, and other complex movement patterns were evoked from domains that had a characteristic organization in both FMC and PPC. Although a PPC domain (e.g. reaching) may be connected with other PPC domains (e.g. grasping and defensive), its connections with FMC are preferential for a matching domain (reaching). Similarly, electrical stimulation of a PPC domain and concurrent optical imaging of FMC, showed activation patterns consistent with the preferential connectivity of PPC and FMC domains. The evidence for similar arrangements of interconnected functional domains in PPC and FMC of members of three major branches of the primate radiation suggests that the parietal–frontal networks emerged early in the evolution of primates. The small size of PPC in the close relatives of primates including lagomorphs, rodents, and tree shrews, suggests a limited involvement of PPC in motor behavior before archaic primates emerged. However, functional domains may have evolved in motor cortex before the emergence of archaic primates.
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DOI：
10.1523/jneurosci.1777-11.2011
发表时间：
2011-08-10
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Gharbawie OA;Stepniewska I;Qi H;Kaas JH
通讯作者：
Kaas JH
DOI：
10.1073/pnas.1031751100
发表时间：
2003-05-13
影响因子：
11.1
作者：
Cooke, DF;Taylor, CSR;Graziano, MSA
通讯作者：
Graziano, MSA
影响因子：
3.7
作者：
Gharbawie, Omar A.;Stepniewska, Iwona;Kaas, Jon H.
通讯作者：
Kaas, Jon H.
影响因子：
5.7
作者：
Durand, Jean-Baptiste;Peeters, Ronald;Orban, Guy A.
通讯作者：
Orban, Guy A.
影响因子：
2.5
作者：
BRUCE, CJ;GOLDBERG, ME
通讯作者：
GOLDBERG, ME