A map of cell type-specific auxin responses.
A map of cell type-specific auxin responses.
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DOI:
10.1038/msb.2013.40
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发表时间:
2013
影响因子:
9.9
通讯作者:
中科院分区:
文献类型:
--
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In plants, changes in local auxin concentrations can trigger a range of developmental processes as distinct tissues respond differently to the same auxin stimulus. However, little is known about how auxin is interpreted by individual cell types. We performed a transcriptomic analysis of responses to auxin within four distinct tissues of the Arabidopsis thaliana root and demonstrate that different cell types show competence for discrete responses. The majority of auxin-responsive genes displayed a spatial bias in their induction or repression. The novel data set was used to examine how auxin influences tissue-specific transcriptional regulation of cell-identity markers. Additionally, the data were used in combination with spatial expression maps of the root to plot a transcriptomic auxin-response gradient across the apical and basal meristem. The readout revealed a strong correlation for thousands of genes between the relative response to auxin and expression along the longitudinal axis of the root. This data set and comparative analysis provide a transcriptome-level spatial breakdown of the response to auxin within an organ where this hormone mediates many aspects of development.
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影响因子:
9.2
作者:
Heisler, MG;Ohno, C;Meyerowitz, EM
通讯作者:
Meyerowitz, EM
影响因子:
56.9
作者:
De Smet, Ive;Vassileva, Valya;Beeckman, Tom
通讯作者:
Beeckman, Tom
影响因子:
9.2
作者:
Bishopp, Anthony;Help, Hanna;Helariutta, Yka
通讯作者:
Helariutta, Yka
影响因子:
4.6
作者:
De Smet, Ive;Tetsumura, Takuya;Beeckman, Tom
通讯作者:
Beeckman, Tom
影响因子:
7.4
作者:
Bargmann, Bastiaan O. R.;Birnbaum, Kenneth D.
通讯作者:
Birnbaum, Kenneth D.