Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.

Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.
复制标题

DOI:
10.1016/j.nantod.2011.04.001
复制
发表时间:
2011-06-01
期刊:
影响因子:
17.4
通讯作者:
Irvine DJ
Irvine DJ
中科院分区:
材料科学1区
文献类型:
--
作者:
Stephan MT;Irvine DJ

文献摘要

参考文献

被引文献

相似文献

基于活细胞注射的治疗方法已应用于癌症、心血管疾病和糖尿病等多种疾病的临床使用和临床前开发中。为了增强治疗细胞的功能,人们正在开发各种化学和材料科学策略,用新分子、人工受体和多功能纳米材料改造治疗细胞的表面,综合赋予供体细胞新的特性和功能。这些方法为增强活细胞功能的传统基因工程策略提供了强有力的补充。
Therapeutic treatments based on the injection of living cells are in clinical use and preclinical development for diseases ranging from cancer to cardiovascular disease to diabetes. To enhance the function of therapeutic cells, a variety of chemical and materials science strategies are being developed that engineer the surface of therapeutic cells with new molecules, artificial receptors, and multifunctional nanomaterials, synthetically endowing donor cells with new properties and functions. These approaches offer a powerful complement to traditional genetic engineering strategies for enhancing the function of living cells.
DOI: 10.1021/nn901319y
发表时间: 2010-02-23
期刊: ACS nano
影响因子: 17.1
作者:
Cheng H;Kastrup CJ;Ramanathan R;Siegwart DJ;Ma M;Bogatyrev SR;Xu Q;Whitehead KA;Langer R;Anderson DG
通讯作者: Anderson DG
DOI: 10.1016/j.biomaterials.2004.07.047
发表时间: 2005-05-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Balthasar, S;Michaelis, K;Langer, K
通讯作者: Langer, K
DOI: 10.1038/nmeth735
发表时间: 2005-02-01
期刊: NATURE METHODS
影响因子: 48
作者:
Chen, I;Howarth, M;Ting, AY
通讯作者: Ting, AY
DOI: 10.1021/nl072209h
发表时间: 2007-12-01
期刊: NANO LETTERS
影响因子: 10.8
作者:
Choi, Mi-Ran;Stanton-Maxey, Katie J.;Clare, Susan E.
通讯作者: Clare, Susan E.
DOI: 10.1038/nm1297
发表时间: 2005-10-01
期刊: NATURE MEDICINE
影响因子: 82.9
作者:
Cole, C;Qiao, J;Vile, RG
通讯作者: Vile, RG