Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.
Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.
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DOI:
10.1016/j.nantod.2011.04.001
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发表时间:
2011-06-01
期刊:
影响因子:
17.4
通讯作者:
Irvine DJ
中科院分区:
文献类型:
--
作者:
Stephan MT;Irvine DJ
Therapeutic treatments based on the injection of living cells are in clinical use and preclinical development for diseases ranging from cancer to cardiovascular disease to diabetes. To enhance the function of therapeutic cells, a variety of chemical and materials science strategies are being developed that engineer the surface of therapeutic cells with new molecules, artificial receptors, and multifunctional nanomaterials, synthetically endowing donor cells with new properties and functions. These approaches offer a powerful complement to traditional genetic engineering strategies for enhancing the function of living cells.
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