A snapshot of smokers after lung and colorectal cancer diagnosis.

A snapshot of smokers after lung and colorectal cancer diagnosis.
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DOI:
10.1002/cncr.26545
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发表时间:
2012-06-15
期刊:
影响因子:
6.2
通讯作者:
Keating NL
Keating NL
中科院分区:
医学1区
文献类型:
--
作者:
Park ER;Japuntich SJ;Rigotti NA;Traeger L;He Y;Wallace RB;Malin JL;Zallen JP;Keating NL

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癌症诊断后继续吸烟可能会对治疗效果、后续癌症风险和生存率产生不利影响。癌症诊断后继续吸烟的流行率研究不足。在多地区癌症护理结果研究和监测队列(肺癌[N=2456],结直肠癌[N=3063])中,我们检查了诊断时和诊断后5个月的吸烟率以及与持续吸烟相关的因素。90.2%的肺癌患者和54.8%的结直肠癌患者曾吸烟。在诊断时,38.7%的肺癌和13.7%的结直肠癌患者吸烟; 14.2%的肺癌和9.0%的结直肠癌患者在诊断后5个月吸烟。与非转移性肺癌患者持续吸烟相关的因素有:医疗保险、其他公共/未指明的保险、未接受化疗、未接受手术、既往心血管疾病、较低的体重指数、较低的情感支持和较高的每日吸烟率(所有p<0.05)。与非转移性结直肠癌患者持续吸烟独立相关的因素是男性、高中学历、无保险、未接受手术和较高的每日吸烟率(所有p<0.05)。诊断后,相当一部分肺癌和结直肠癌患者继续吸烟。肺癌患者在诊断时和诊断后吸烟率较高;结直肠癌患者在诊断后戒烟的可能性较小。与持续吸烟相关的因素在两组之间存在差异。未来的戒烟努力应该检查癌症类型的差异,特别是当比较吸烟是一个明确的风险因素的癌症与吸烟不是的癌症时。
Continued smoking after cancer diagnosis may adversely affect treatment effectiveness, subsequent cancer risk, and survival. The prevalence of continued smoking following cancer diagnosis is understudied. In the multi-regional Cancer Care Outcomes Research and Surveillance cohort (lung cancer [N=2456], colorectal cancer [N=3063]), we examined smoking rates at diagnosis and 5 months following diagnosis and factors associated with continued smoking. 90.2% of lung and 54.8% of colorectal cancer patients reported ever smoking. At diagnosis, 38.7% of lung cancer and 13.7% of colorectal cancer patients were smoking; 14.2% of lung cancer and 9.0% of colorectal cancer patients were smoking 5 months post-diagnosis. Factors associated with continued smoking among non-metastatic lung cancer patients were: Medicare, other public/unspecified insurance, not having chemotherapy, not having surgery, prior cardiovascular disease, lower body mass index, lower emotional support, and higher ever daily smoking rates (all p<.05). Factors independently associated with continued smoking among non-metastatic colorectal cancer patients were male sex, high school education, being uninsured, not having surgery, and higher ever daily smoking rates (all p<.05). Following diagnosis, a substantial minority of lung and colorectal cancer patients continue smoking. Lung cancer patients had higher rates of smoking at diagnosis and following diagnosis; colorectal cancer patients were less likely to quit smoking following diagnosis. Factors associated with continued smoking differed between the two groups. Future smoking cessation efforts should examine differences by cancer type, particularly when comparing cancers for which smoking is a well established risk factor versus cancers for which it is not.
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