Synthesis of β-cyclodextrin conjugated superparamagnetic iron oxide nanoparticles for selective binding and detection of cholesterol crystals.

Synthesis of β-cyclodextrin conjugated superparamagnetic iron oxide nanoparticles for selective binding and detection of cholesterol crystals.
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β-环糊精联合的超帕磁铁氧化铁纳米颗粒的合成,用于选择性结合和检测胆固醇晶体。

DOI:
10.1039/c2cc17852d
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发表时间:
2012-04-07
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Huang X
Huang X
中科院分区:
其他
文献类型:
--
作者:
Li H;El-Dakdouki MH;Zhu DC;Abela GS;Huang X

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构建了β-环糊精偶联的水溶性超顺磁性纳米粒子。这些颗粒显示出与胆固醇晶体的选择性结合,这为磁共振成像(MRI)检测与胆固醇晶体相关的疾病打开了大门。
Water-soluble, β-cyclodextrin conjugated superparamagnetic nanoparticles have been constructed. These particles showed selective binding to cholesterol crystals, which opens the door for the detection of cholesterol crystal-related diseases such as atherosclerosis by magnetic resonance imaging (MRI).
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