Thalamic Deep Brain Stimulation for Parkinson’s Disease
Thalamic Deep Brain Stimulation for Parkinson’s Disease
复制标题
丘脑深部脑刺激治疗帕金森病
DOI:
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发表时间:
2011
期刊:
影响因子:
--
通讯作者:
Satoshi Goto
中科院分区:
文献类型:
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作者:
R. Morigaki;Shinji Nagahiro;Ryuji Kaji;Satoshi Goto
With recent advances in neuroimaging and neurosurgical techniques as well as better understanding of functional motor brain circuits, there is increasing evidence that electrical deep brain stimulation (DBS) can be a powerful and safe therapeutic option for medically intractable movement disorders and neuropsychiatric diseases. For more than half a century, the ventrolateral (VL) nucleus of the thalamus has been an anatomical target for stereotactic surgeries (e.g., ablation surgery and DBS) treating various types of tremors, including Parkinson’s disease (PD)-associated tremor. The VL nucleus comprises the nucleus ventralis intermedius (Vim) and the nucleus ventralis oralis (Vo) (Hassler, 1959). Currently, thalamic DBS is widely used because of its reversibility, adjustability, and low level of invasiveness. Thalamic DBS of the Vim nucleus can effectively alleviate parkinsonian tremor; however, it does not provide consistent improvement in parkinsonian symptoms other than tremor. Therefore, its use is limited to patients with tremorpredominant PD, in whom other motor symptoms are not disabling. In this review, we will survey the rationale and current use of thalamic DBS in the treatment of PD.
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影响因子:
14.5
作者:
LENZ, FA;KWAN, HC;LENZ, YE
通讯作者:
LENZ, YE
DOI:
--
发表时间:
1998
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
--
作者:
Seibyl,JP;Marek,K;Sheff,K;Zoghbi,S;Baldwin,RM;Charney,DS;vanDyck,CH;Innis,RB
通讯作者:
Innis,RB
影响因子:
2.5
作者:
Godwin, DW;Vaughan, JW;Sherman, SM
通讯作者:
Sherman, SM
影响因子:
2.5
作者:
Hurtado, JA;Rubchinsky, LL;Pappas, CTE
通讯作者:
Pappas, CTE