A semi-parametric Bayesian model for semi-continuous longitudinal data.
A semi-parametric Bayesian model for semi-continuous longitudinal data.
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DOI:
10.1002/sim.9359
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发表时间:
2022-06-15
影响因子:
2
通讯作者:
Thompson, Wesley K.
中科院分区:
文献类型:
--
作者:
Ren, Junting;Tapert, Susan;Fan, Chun Chieh;Thompson, Wesley K.
Semi-continuous data present challenges in both model fitting and interpretation. Parametric distributions may be inappropriate for extreme long right tails of the data. Mean effects of covariates, susceptible to extreme values, may fail to capture relevant information for most of the sample. We propose a two-component semi-parametric Bayesian mixture model, with the discrete component captured by a probability mass (typically at zero) and the continuous component of the density modeled by a mixture of B-spline densities that can be flexibly fit to any data distribution. The model includes random effects of subjects to allow for application to longitudinal data. We specify prior distributions on parameters and perform model inference using a Markov Chain Monte Carlo (MCMC) Gibbs-sampling algorithm programmed in R. Statistical inference can be made for multiple quantiles of the covariate effects simultaneously providing a comprehensive view. Various MCMC sampling techniques are used to facilitate convergence. We demonstrate the performance and the interpretability of the model via simulations and analyses on the National Consortium on Alcohol and Neurodevelopment in Adolescence study (NCANDA) data on alcohol binge drinking.
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DOI:
10.1534/g3.115.021154
发表时间:
2015-08-18
期刊:
G3 (Bethesda, Md.)
影响因子:
--
作者:
Montesinos-López OA;Montesinos-López A;Crossa J;Burgueño J;Eskridge K
通讯作者:
Eskridge K
影响因子:
2.2
作者:
Chib, S;Carlin, BP
通讯作者:
Carlin, BP
DOI:
10.15288/jsa.1998.59.427
发表时间:
1998-07-01
期刊:
JOURNAL OF STUDIES ON ALCOHOL
影响因子:
--
作者:
Brown, SA;Myers, MG;Vik, PW
通讯作者:
Vik, PW
影响因子:
3.4
作者:
Brown, Sandra A.;Brumback, T. Y.;Tapert, Susan F.
通讯作者:
Tapert, Susan F.
影响因子:
2.4
作者:
Ruppert, D
通讯作者:
Ruppert, D