Mitochondrial-nuclear crosstalk is involved in oxygen-regulated gene expression in yeast.

Mitochondrial-nuclear crosstalk is involved in oxygen-regulated gene expression in yeast.
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线粒体-核串扰参与酵母中氧调节基因的表达。

DOI:
10.1007/0-306-46825-5_17
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发表时间:
2000
影响因子:
--
通讯作者:
Dagsgaard,CJ
Dagsgaard,CJ
中科院分区:
医学4区
文献类型:
--
作者:
Poyton,RO;Dagsgaard,CJ

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酿酒酵母中几个氧调节核基因的表达受到线粒体的影响。最近的证据表明线粒体有两个层面的参与。一方面,线粒体呼吸功能对于某些缺氧基因的缺氧诱导至关重要。另一方面,线粒体基因组本身的功能独立于其呼吸功能,在一些需氧基因的最佳表达中。这些发现表明线粒体释放至少两种类型的“信号”,这些信号在氧调节基因的表达中发挥作用。
The expression of several oxygen-regulated nuclear genes in the yeastSaccharomyces cerevisiaeis affected by the mitochondrion. Recent evidence suggests two levels of mitochondrial involvement. On the one hand, mitochondrial respiratory function is essential for the anoxic induction of somehypoxicgenes. On the other hand, the mitochondrial genome itself functions independently of its respiratory function, in the optimal expression of someaerobicgenes. These findings suggest that the mitochondrion release at least two types of ‘signals’ that function in the expression of oxygen-regulated genes.
DOI: 10.1021/bi00458a004
发表时间: 1990-02-13
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
AGELLON, LB;QUINET, EM;TALL, AR
通讯作者: TALL, AR
DOI: 10.1093/oxfordjournals.jbchem.a135418
发表时间: 1985-01-01
影响因子: 2.7
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DOI: 10.1126/science.2999980
发表时间: 1985-01-01
期刊: SCIENCE
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