Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes.
Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes.
复制标题
2 型糖尿病男性的咖啡摄入量与心血管疾病和全因死亡率的风险。
DOI：
10.2337/dc08-2251
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发表时间：
2009-06
期刊：
影响因子：
16.2
通讯作者：
van Dam RM
中科院分区：
文献类型：
--
作者：
Zhang W;Lopez-Garcia E;Li TY;Hu FB;van Dam RM
咖啡的摄入与有害的急性代谢和血液动力学效应有关。我们调查了咖啡消费与男性糖尿病患者心血管疾病风险和死亡率的关系。我们进行了一项前瞻性队列研究，包括3，497名基线时无CVD的糖尿病男性。校正年龄、吸烟和其他心血管危险因素后，与不喝咖啡的人相比，每天喝≥4杯含咖啡因咖啡的人心血管疾病的相对风险（RR）为0.88（95% CI 0.50-1.57）（趋势P = 0.29），全因死亡率的相对风险（RR）为0.80（0.41-1.54）（趋势P = 0.45）。按吸烟和糖尿病持续时间分层也得到了类似的结果。最高五分位数与最低五分位数相比，咖啡因摄入量对CVD的RR为1.02（0.70-1.47;趋势P = 0.96），对死亡率的RR为0.96（0.64-1.44;趋势P = 0.69）。这些数据表明，经常饮用咖啡与糖尿病男性心血管疾病或死亡率的风险增加无关。
Coffee consumption has been linked to detrimental acute metabolic and hemodynamic effects. We investigated coffee consumption in relation to risk of CVDs and mortality in diabetic men. We conducted a prospective cohort study including 3,497 diabetic men without CVD at baseline. After adjustment for age, smoking, and other cardiovascular risk factors, relative risks (RRs) were 0.88 (95% CI 0.50–1.57) for CVDs (P for trend = 0.29) and 0.80 (0.41–1.54) for all-cause mortality (P for trend = 0.45) for the consumption of ≥4 cups/day of caffeinated coffee compared with those for non–coffee drinkers. Stratification by smoking and duration of diabetes yielded similar results. RRs for caffeine intake for the highest compared with the lowest quintile were 1.02 (0.70–1.47; P for trend = 0.96) for CVDs and 0.96 (0.64–1.44; P for trend = 0.69) for mortality. These data indicate that regular coffee consumption is not associated with increased risk for CVDs or mortality in diabetic men.
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