Does the cortisol response to stress mediate the link between expressed emotion and oppositional behavior in Attention-Deficit/Hyperactivity-Disorder (ADHD)?

Does the cortisol response to stress mediate the link between expressed emotion and oppositional behavior in Attention-Deficit/Hyperactivity-Disorder (ADHD)?
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DOI:
10.1186/1744-9081-6-45
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发表时间:
2010-07-15
期刊:
Behavioral and brain functions : BBF
影响因子:
--
通讯作者:
Sonuga-Barke EJ
Sonuga-Barke EJ
中科院分区:
其他
文献类型:
--
作者:
Christiansen H;Oades RD;Psychogiou L;Hauffa BP;Sonuga-Barke EJ

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表达情绪 (EE) 与患有注意力缺陷/多动症 (ADHD) 的儿童的对抗行为 (OPB) 相关。 EE 与某些疾病的应激反应改变有关,但 ADHD 尚未得到研究。我们检验了这样的假设:ADHD 中的 OPB 是由与压力相关的皮质醇对 EE 反应性改变介导的。两组儿童(患有/不患有多动症)及其各自的父母被随机分配到有/没有负面情绪的两种不同条件下,并参与情绪激发任务。测量了父母的 EE、他们对孩子的 OPB 的评分以及孩子的唾液皮质醇水平。父母的低热情与 ADHD 中的 OPB 相关。高水平的父母 EE 会引发更大的皮质醇反应。与压力相关的皮质醇反应介导了所有儿童的 EE-OPB 联系。这凸显了亲子互动对于外化行为问题的普遍重要性。高 EE 是 ADHD 儿童的一个显着压力源,会导致皮质醇和 OPB 水平升高。 OPB 的发生可能是由对高 EE 的应激反应介导的。
Expressed Emotions (EE) are associated with oppositional behavior (OPB) in children with Attention Deficit/Hyperactivity Disorder (ADHD). EE has been linked to altered stress responses in some disorders, but ADHD has not been studied. We test the hypothesis that OPB in ADHD is mediated by altered stress-related cortisol reactivity to EE. Two groups of children (with/without ADHD) and their respective parents were randomly assigned to two different conditions with/without negative emotion and participated in an emotion provocation task. Parents' EE, their ratings of their children's OPB and their children's salivary cortisol levels were measured. Low parental warmth was associated with OPB in ADHD. High levels of parental EE elicited a larger cortisol response. Stress-related cortisol reactivity mediated the EE-OPB link for all children. This highlights the general importance of parent-child interactions on externalizing behavior problems. High EE is a salient stressor for ADHD children that leads to increased levels of cortisol and OPB. The development of OPB might be mediated by the stress-response to high EE.
DOI: 10.1037/0022-3514.51.6.1173
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影响因子: 7.6
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发表时间: 1996-12-01
期刊: CHILD DEVELOPMENT
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