Challenges in pediatric neuroimaging.

Challenges in pediatric neuroimaging.
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DOI:
10.1016/j.neuroimage.2018.04.044
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发表时间:
2019-01-15
期刊:
影响因子:
5.7
通讯作者:
Xu D
Xu D
中科院分区:
医学1区
文献类型:
--
作者:
Barkovich MJ;Li Y;Desikan RS;Barkovich AJ;Xu D

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由于发育中的大脑结构、代谢和功能的快速变化,儿科神经成像是具有挑战性的。由于儿童体型较小和不成熟,需要一个受过专门培训的团队来制作高质量的诊断图像。病人的行动、合作和医疗条件决定了所使用的方法和设备。根据每个儿童的年龄和功能状况量身定做的方法以及专职工作人员、成像硬件和软件的适当组合是关键;这些方法从低技术含量的技术(如喂奶和婴儿床)到专门的小径MRI扫描仪、MRI兼容保温箱和新生儿头部线圈。新的前后处理技术还可以弥补运动伪影和低信号,这些往往会降低新生儿扫描的质量。
Pediatric neuroimaging is challenging due the rapid structural, metabolic, and functional changes that occur in the developing brain. A specially trained team is needed to produce high quality diagnostic images in children, due to their small physical size and immaturity. Patient motion, cooperation and medical condition dictate the methods and equipment used. A customized approach tailored to each child’s age and functional status with the appropriate combination of dedicated staff, imaging hardware, and software is key; these range from low-tech techniques, such as feed and swaddle, to specialized small bore MRI scanners, MRI compatible incubators and neonatal head coils. New pre-and post-processing techniques can also compensate for the motion artifacts and low signal that often degrade neonatal scans.
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