Complex Organization in Multicellularity as a Necessity in Evolution
Complex Organization in Multicellularity as a Necessity in Evolution
复制标题
多细胞中的复杂组织是进化的必要条件
作者:
C. Furusawa;K. Kaneko
By introducing a dynamical system model of a multicellular system, it is shown that an organism with a variety of differentiated cell types and a complex pattern emerges through cell-cell interactions even without postulating any elaborate control mechanism. Such an organism is found to maintain a larger growth speed as an ensemble, by achieving a cooperative use of resources, than do simple homogeneous cells, which behave selfishly. This suggests that the emergence of multicellular organisms with complex organization is a necessity in evolution. According to our theoretical model, there initially appear multipotent stem cells, which undergo stochastic differentiation to other cell types. With development and differentiation, both the chemical diversity and the complexity of intra-cellular dynamics are decreased, as a general consequence of our system. Robustness of the developmental process is also confirmed.
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影响因子:
20.3
作者:
M. Ogawa
通讯作者:
M. Ogawa
影响因子:
56.9
作者:
Yoon, HS;Golden, JW
通讯作者:
Golden, JW
DOI:
10.1016/s0074-7696(08)61428-x
发表时间:
1986
期刊:
International review of cytology
影响因子:
--
作者:
Kirk,DL;Harper,JF
通讯作者:
Harper,JF
DOI:
10.1242/dev.112.2.571
发表时间:
1991
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Tam,LW;Kirk,DL
通讯作者:
Kirk,DL