Distance and destination of retail meat alter multidrug resistant contamination in the United States food system.
Distance and destination of retail meat alter multidrug resistant contamination in the United States food system.
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DOI：
10.1038/s41598-023-48197-z
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发表时间：
2023-11-29
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
抗生素耐药性感染是一个全球性问题，尤其是由多重耐药（MDR）细菌引起的感染，多重耐药细菌是指对三类以上药物耐药的细菌。畜牧业通过受污染的零售肉类加剧了食源性抗微生物疾病的负担。在美国，零售肉类在全国范围内运输。因此，了解影响多重耐药细菌污染的地理空间因素对于保护消费者和制定干预措施至关重要。利用美国食品药品监督管理局国家抗微生物耐药性监测系统（NARMS）提供的数据，我们通过加工商和零售商的位置描述了零售肉类的运输距离，并使用对数二项式回归将该距离作为多重耐药细菌肉类污染的一个风险因素进行了研究。2012 - 2014年期间收集的肉类样本共计11243个，其中4791个（42.61%）被细菌污染，这些细菌中有835个（17.43%）是多重耐药菌。所有研究的地理空间因素都与多重耐药细菌肉类污染有关。在对年份和肉类类型进行调整后，我们发现南方加工的肉类（与次高地区相比，调整后的相对患病率比[aPR]为1.35；95%置信区间为1.06 - 1.73）、在马里兰州销售的肉类（与次高州相比，aPR为1.12；95%置信区间为0.95 - 1.32）以及运输距离在194到469英里的肉类（与运输距离<194英里的肉类相比，aPR为1.59；95%置信区间为1.31 - 1.94）中多重耐药污染的患病率较高。然而，敏感性分析显示，纽约销售的肉类中多重耐药沙门氏菌污染的患病率最高（4.84%）。在对NARMS数据的二次分析中，产品销售的地理位置和运输距离都与零售肉类的微生物污染有关。
Antibiotic-resistant infections are a global concern, especially those caused by multidrug-resistant (MDR) bacteria, defined as those resistant to more than three drug classes. The animal agriculture industry contributes to the antimicrobial resistant foodborne illness burden via contaminated retail meat. In the United States, retail meat is shipped across the country. Therefore, understanding geospatial factors that influence MDR bacterial contamination is vital to protect consumers and inform interventions. Using data available from the United States Food and Drug Administration’s National Antimicrobial Resistance Monitoring System (NARMS), we describe retail meat shipping distances using processor and retailer locations and investigated this distance as a risk factor for MDR bacteria meat contamination using log-binomial regression. Meat samples collected during 2012–2014 totaled 11,243, of which 4791 (42.61%) were contaminated with bacteria and 835 (17.43%) of those bacteria were MDR. All examined geospatial factors were associated with MDR bacteria meat contamination. After adjustment for year and meat type, we found higher prevalence of MDR contamination among meat processed in the south (relative adjusted prevalence ratio [aPR] 1.35; 95% CI 1.06–1.73 when compared to the next-highest region), sold in Maryland (aPR 1.12; 95% CI 0.95–1.32 when compared to the next-highest state), and shipped from 194 to 469 miles (aPR 1.59; 95% CI 1.31–1.94 when compared to meats that traveled < 194 miles). However, sensitivity analyses revealed that New York sold the meat with the highest prevalence of MDR Salmonella contamination (4.84%). In this secondary analysis of NARMS data, both geographic location where products were sold and the shipping distance were associated with microbial contamination on retail meat.
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影响因子：
5.2
作者：
Ham, Yoo-Geun;Kug, Jong-Seong;Park, Jong-Yeon
通讯作者：
Park, Jong-Yeon
影响因子：
8
作者：
Capotondi, Antonietta;Wittenberg, Andrew T.;Yeh, Sang-Wook
通讯作者：
Yeh, Sang-Wook
影响因子：
4.8
作者：
Aceituno, Patricio;del Rosario Prieto, Maria;Falvey, Mark
通讯作者：
Falvey, Mark
影响因子：
18.3
作者：
Freund, Mandy B.;Henley, Benjamin J.;Dommenget, Dietmar
通讯作者：
Dommenget, Dietmar
影响因子：
4.6
作者：
Dewitte, Boris;Takahashi, Ken
通讯作者：
Takahashi, Ken