Reconstruction of fully three-dimensional high spatial and temporal resolution MR temperature maps for retrospective applications.

Reconstruction of fully three-dimensional high spatial and temporal resolution MR temperature maps for retrospective applications.
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DOI:
10.1002/mrm.23055
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发表时间:
2012-03
影响因子:
3.3
通讯作者:
Parker, Dennis L.
Parker, Dennis L.
中科院分区:
医学3区
文献类型:
--
作者:
Todd, Nick;Vyas, Urvi;de Bever, Josh;Payne, Allison;Parker, Dennis L.

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Many areas of MR-guided thermal therapy research would benefit from temperature maps with high spatial and temporal resolution that cover a large 3-D volume. This paper describes an approach to achieve these goals that is suitable for research applications where retrospective reconstruction of the temperature maps is acceptable. The method acquires undersampled data from a modified 3-D segmented EPI sequence and creates images using a temporally constrained reconstruction algorithm. The 3-D images can be zero-filled to arbitrarily small voxel spacing in all directions and then converted into temperature maps using the standard proton resonance frequency (PRF) shift technique. During HIFU heating experiments, the proposed method was used to obtain temperature maps with 1.5×1.5×3.0 mm resolution, 288×162×78 mm field of view, and 1.7 second temporal resolution. The approach is validated to demonstrate that it can accurately capture the spatial characteristics and time dynamics of rapidly changing HIFU-induced temperature distributions. Example applications from MR-guided high intensity focused ultrasound research are shown to demonstrate the benefits of the large coverage fully 3-D temperature maps, including characterization of volumetric heating trajectories and near-and far-field heating.
DOI: 10.1002/mrm.21248
发表时间: 2007-06-01
影响因子: 3.3
作者:
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影响因子: 19.7
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