Clinical Cerenkov luminescence imaging of (18)F-FDG.

Clinical Cerenkov luminescence imaging of (18)F-FDG.
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DOI:
10.2967/jnumed.113.127266
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发表时间:
2014-01
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
--
通讯作者:
Grimm J
Grimm J
中科院分区:
其他
文献类型:
--
作者:
Thorek DL;Riedl CC;Grimm J

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The aim of this study was to determine the feasibility of Cerenkov luminescence (CL) imaging of patients undergoing diagnostic 18F-FDG scans to detect nodal disease. Patients undergoing routine 18F-FDG PET/CT for various malignancies consented to being scanned for CL. White-light and Cerenkov images (5-min acquisition) of the surface of the patient contralateral to and at the site of nodal 18F-FDG uptake were acquired using a cooled, intensified charge-coupled-device camera. The camera demonstrated linear correlation between activity and counts into the low nanocurie range using 18F-FDG. Imaging of patients revealed the presence of 18F-FDG uptake in nodes that demonstrated uptake on PET. A correlation between maximum standardized uptake value from PET and counting rate per area on the CL imaging was established. CL imaging with diagnostic doses of 18F-FDG is feasible and can aid in detecting disease in the clinical setting.
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发表时间: 2012-04-01
影响因子: 3.5
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发表时间: 2012-09
期刊: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子: --
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