Immune Regulation in Pregnancy: A Matter of Perspective?

Immune Regulation in Pregnancy: A Matter of Perspective?
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DOI:
10.1016/j.ogc.2016.07.004
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发表时间:
2016-12
影响因子:
3.2
通讯作者:
Bonney EA
Bonney EA
中科院分区:
医学3区
文献类型:
--
作者:
Bonney EA

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母体免疫系统是复杂的,受多种激素和代谢因素的控制,包括通过胎儿提供给她的那些。理解母体耐受和胎儿保护之间的平衡可能需要从多种理论方法来思考免疫激活和耐受的一般问题。这个过程的基础在这里讨论,并可能建议在人类和动物模型的特定实验和免疫系统相关疾病的妊娠患者的特定干预措施。
The maternal immune system is complex and governed by multiple hormonal and metabolic factors, including those provided to her via the fetus. Understanding of the balance between maternal tolerance and protection of the fetus may require thinking from multiple theoretical approaches to general problem of immune activation and tolerance. The basics for this process are discussed here and may suggest both specific experiments in human and animal models and specific interventions in pregnant patients with immune system-related disease.
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