Bilateral Dysfunction of Otolith Pathway in Patients With Unilateral Idiopathic BPPV Detected by ACS-VEMPs.
Bilateral Dysfunction of Otolith Pathway in Patients With Unilateral Idiopathic BPPV Detected by ACS-VEMPs.
复制标题
ACS-VEMPS检测到的单侧特发性BPPV患者耳石途径的双侧功能障碍。
DOI：
10.3389/fneur.2022.921133
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发表时间：
2022
影响因子：
3.4
通讯作者：
Zhang, Qing
中科院分区：
文献类型：
--
作者：
Niu, Xiaorong;Han, Peng;Duan, Maoli;Chen, Zichen;Hu, Juan;Chen, Yanfei;Xu, Min;Ren, Pengyu;Zhang, Qing
关键词：
结合空气传导声诱发颈前庭诱发肌电位（acs - cemp）和眼前庭诱发肌电位（ACS-oVEMP）观察单侧特发性良性阵发性体位性眩晕（BPPV）患者耳石通路的功能状态。180名BPPV患者接受了常规cemp和oVEMP测试。比较BPPV患者与对照组的vemp异常率。BPPV患者患耳cemp和oVEMP异常率分别为46.7%（84/180）和57.2%(103/180)，未患耳cemp和oVEMP异常率分别为45.0%（81/180）和56.7% (102/180)；与正常对照耳cemp和oVEMP的异常率相比，均显著增高。与正常受试者相比，BPPV患者患耳和未患耳的cemp反应率较低。后半规管BPPV患者cVEMP和oVEMP异常率分别为48.1%（76/158）和57.6%(91/158)，外侧半规管BPPV患者cVEMP和oVEMP异常率分别为36.4%（8/22）和54.5%（12/22）。后半规管BPPV与外侧半规管BPPV的VEMP异常无显著差异。BPPV患者患耳和未患耳的cemps和oVEMPs异常发生率均显著高于对照组。单侧特发性BPPV的病理机制可能与双侧耳石通路变性有关。
To observe the functional status of the otolith pathway in patients with unilateral idiopathic benign paroxysmal positional vertigo (BPPV) by combining air-conducted sound elicited cervical vestibular-evoked myogenic potential (ACS-cVEMP) and ocular vestibular-evoked myogenic potential (ACS-oVEMP). One hundred and eighty patients with BPPV were recruited for conventional cVEMP and oVEMP tests. The abnormal rates of VEMPs were compared between BPPV patients and control participants. The abnormal rates of cVEMP and oVEMP in BPPV patients were 46.7% (84/180) and 57.2% (103/180) in affected ears, respectively, and 45.0% (81/180) and 56.7% (102/180) in unaffected ears, respectively; both were significantly higher than the abnormal rates of cVEMP and oVEMP in normal control ears. Compared with normal subjects, the cVEMP response rate was lower in affected and unaffected ears in BPPV patients. The abnormal rates of cVEMP and oVEMP were 48.1% (76/158) and 57.6% (91/158) in patients with posterior semicircular canal BPPV, and 36.4% (8/22) and 54.5% (12/22) in lateral semicircular canal BPPV. There was no significant difference in VEMP abnormalities between posterior semicircular canal BPPV and lateral semicircular canal BPPV. The prevalence of abnormal cVEMPs and oVEMPs in both affected and unaffected ears of patients with BPPV was significantly higher than that observed in the control group. The pathological mechanism of unilateral idiopathic BPPV may be associated with bilateral degeneration of otolith pathways.
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影响因子：
1.4
作者：
Bremova T;Bayer O;Agrawal Y;Kremmyda O;Brandt T;Teufel J;Strupp M
通讯作者：
Strupp M
影响因子：
2.6
作者：
Jang, Yoon Seok;Hwang, Chan Ho;Kim, Lee Suk
通讯作者：
Kim, Lee Suk
影响因子：
2.6
作者：
Kao, Wee Tin K.;Parnes, Lorne S.;Chole, Richard A.
通讯作者：
Chole, Richard A.
影响因子：
0.6
作者：
Mendes, Tihana;Maslovara, Sinisa;Soldo, Silva Butkovic
通讯作者：
Soldo, Silva Butkovic
影响因子：
2.5
作者：
Seo, Toru;Saka, Naoki;Sakagami, Masafumi
通讯作者：
Sakagami, Masafumi