The role of glottal surface adhesion on vocal folds biomechanics.
The role of glottal surface adhesion on vocal folds biomechanics.
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DOI：
10.1007/s10237-014-0603-7
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发表时间：
2015-04
影响因子：
3.5
通讯作者：
Siegmund, Thomas
中科院分区：
文献类型：
--
作者：
Bhattacharya, Pinaki;Siegmund, Thomas
呼吸道表面液体(ASL)是一层非常薄的粘液层，覆盖在声带(VF)表面。当VFS在碰撞后分离时，由ASL介导的粘连发生在发声过程中。这种粘附性是为了确定语音质量和健康状况而假设的。然而，对VF振荡过程中的粘连过程缺乏生物力学的了解。本文对包括接触和粘着的自持振动进行了计算研究。VF结构模型和声门气流被认为是完全三维的。ASL的力学行为通过粘膜粘连强度、粘结能和断裂长度进入的本构牵引-分离定律来描述。所考虑的内聚能值受标准温度和压力下水的内聚能的限制。所考虑的粘合强度值被先前报道的关于大鼠小肠粘膜表面粘连强度的数据约束在上面。该模型在分析中引入了机械长度标尺。VF动力学的各个方面，如流量下降速率、粘合条件下的VF分离以及多个局部流体桥的形成，都与特定的ASL粘接剂性能有关。研究发现，对于所考虑的ASL，VF分离过程的特征是脱键型的。不稳定性导致键区分裂成几个较小的键片。这一发现与体内观察结果一致。
The airway surface liquid (ASL) is a very thin mucus layer and covers the vocal fold (VF) surface. Adhesion mediated by the ASL occurs during phonation as the VFs separate after collision. Such adhesion is hypothesized to determine voice quality and health. However, biomechanical insights into the adhesive processes during VF oscillation are lacking. Here, a computational study is reported on self-sustained VF vibration involving contact and adhesion. The VF structural model and the glottal airflow are considered fully three-dimensional. The mechanical behavior of the ASL is described through a constitutive traction–separation law where mucosal cohesive strength, cohesive energy and rupture length enter. Cohesive energy values considered are bound below by the cohesive energy of water at standard temperature and pressure. Cohesive strength values considered are bound above by prior reported data on the adhesive strength of mucosal surface of rat small intestine. This model introduces a mechanical length scale into the analysis. The sensitivity of various aspects of VF dynamics such as flow-declination rate, VF separation under adhesive condition and formation of multiple local fluid bridges is determined in relation to specific ASL adhesive properties. It is found that for the ASL considered here, the characteristics of the VF separation process are of debond type. Instabilities lead to the breakup of the bond area into several smaller bond patches. Such finding is consistent with in-vivo observations.
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影响因子：
3.9
作者：
Ghatak, A;Chaudhury, MK
通讯作者：
Chaudhury, MK
DOI：
10.1007/s00429-002-0255-8
发表时间：
2002-07-01
期刊：
ANATOMY AND EMBRYOLOGY
影响因子：
--
作者：
Kutta, H;Steven, P;Paulsen, F
通讯作者：
Paulsen, F
使用原子力显微镜进行表面力和粘附的理论模型及其测量。
影响因子：
5.6
作者：
Leite FL;Bueno CC;Da Róz AL;Ziemath EC;Oliveira ON
通讯作者：
Oliveira ON
影响因子：
2.4
作者：
Scherer, RC;Shinwari, D;Afjeh, AA
通讯作者：
Afjeh, AA
影响因子：
2.2
作者：
Ayache, S;Ouaknine, M;Giovanni, A
通讯作者：
Giovanni, A