The MoCA and MMSE as screeners for cognitive impairment in a heart failure population: a study with comprehensive neuropsychological testing.
The MoCA and MMSE as screeners for cognitive impairment in a heart failure population: a study with comprehensive neuropsychological testing.
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DOI：
10.1016/j.hrtlng.2014.05.011
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发表时间：
2014-09
期刊：
影响因子：
2.8
通讯作者：
Hughes, Joel W.
中科院分区：
文献类型：
--
作者：
Hawkins, Misty A. W.;Gathright, Emily C.;Gunstad, John;Dolansky, Mary A.;Redle, Joseph D.;Josephson, Richard;Moore, Shirley M.;Hughes, Joel W.
目的：研究简易精神状态检查(MMSE)和蒙特利尔认知评估(MoCA)检测心力衰竭(HF)患者认知功能障碍的能力。虽然MMSE和MoCA是心力衰竭常用的筛查工具，但还没有研究团队在神经心理测试中证实它们的表现。受试者为106名心力衰竭患者(男性占49.1%，年龄为68.13±9.82岁)，他们完成了MoCA、MMSE和完整的神经心理学测验。检测灵敏度和特异度。判别函数分析测试了筛查者是否正确地检测到认知障碍。MoCA评分为25分，MMSE评分为28分时，敏感度/特异度最佳(分别为.64/.66和.70/.66)。MMSE分类正确率为68%，Wilk‘s Lambda=.87，χ2(1)=14.26，p<；.001。在心力衰竭患者中，MoCA和MMSE均可用于识别大多数有或无认知损害的患者。这两种测试都错误地对大约三分之一的患者进行了分类，因此在筛查的同时需要继续监测和评估患者。
To examine the ability of the Mini Mental Status Examination (MMSE) and Montreal Cognitive Assessment (MoCA) to detect cognitive impairment in persons with heart failure (HF). Although the MMSE and MoCA are commonly used screeners in HF, no research team has validated their performance against neuropsychological testing. Participants were 106 patients with HF (49.1% male, 68.13±9.82 years) who completed the MoCA, MMSE, and a full neuropsychological battery. Sensitivity and specificity were examined. Discriminant function analyses tested whether the screeners correctly detected cognitive impairment. A MoCA score <25 and MMSE score of <28 yielded optimal sensitivity/specificity (.64/.66 and .70/.66, respectively). The MoCA correctly classified 65% of patients, Wilk's lambda=.91, χ2(1)=9.89, p<.01, and the MMSE correctly classified 68%, Wilk's lambda=.87, χ2(1)=14.26, p<.001. In HF, both the MoCA and MMSE are useful in identifying the majority of patients with and without cognitive impairment. Both tests misclassified approximately one-third of patients, so continued monitoring and evaluation of patients is needed in conjunction with screening.
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2.9
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