A cortical core for dynamic integration of functional networks in the resting human brain.

A cortical core for dynamic integration of functional networks in the resting human brain.
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DOI:
10.1016/j.neuron.2012.03.031
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发表时间:
2012-05-24
期刊:
影响因子:
16.2
通讯作者:
Corbetta M
Corbetta M
中科院分区:
医学1区
文献类型:
--
作者:
de Pasquale F;Della Penna S;Snyder AZ;Marzetti L;Pizzella V;Romani GL;Corbetta M

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We used magneto-encephalography to study the temporal dynamics of band-limited power correlation at rest within and across six brain networks previously defined by prior fMRI studies. Epochs of transiently high within-network BLP correlation were identified and correlation of BLP time-series across networks was assessed in these epochs. These analyses demonstrate that functional networks are not equivalent with respect to cross-network interactions. The default-mode network and the posterior cingulate cortex, in particular, exhibit the highest degree of transient BLP correlation with other networks especially in the 14–25 Hz (beta band) frequency range. Our results indicate that the previously demonstrated neuroanatomical centrality of the PCC and DMN has a physiological counterpart in the temporal dynamics of network interaction at behaviorally relevant time scales. This interaction involved subsets of nodes from other networks during periods in which their internal correlation was low.
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