From urothelial signalling to experiencing a sensation related to the urinary bladder.

From urothelial signalling to experiencing a sensation related to the urinary bladder.
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DOI:
10.1111/apha.12011
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发表时间:
2013-01
期刊:
Acta physiologica (Oxford, England)
影响因子:
--
通讯作者:
Wyndaele JJ
Wyndaele JJ
中科院分区:
其他
文献类型:
--
作者:
Birder L;Wyndaele JJ

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膀胱感觉的机制以及我们在正常排尿和病理过程中体验感觉的方式是复杂的并且尚未被很好地理解。在储存和排空期间,膀胱壁内多种细胞类型(即尿上皮和膀胱传入细胞)发生的机械变化会对我们的感觉系统产生重大影响。在这篇综述中,我们讨论膀胱感觉,重点关注外围的编码事件。
The mechanisms underlying bladder sensation and the way we experience sensations during normal voiding and in pathology is complex and not well understood. During storage and emptying, mechanical changes occurring in number of cell types within the bladder wall (i.e. the uroepithelium and bladder afferents) can have a major influence on our sensory systems. In this review, we discuss bladder sensation with a focus on coding events in the periphery.
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