Plasma fluorescent oxidation products and short-term occupational particulate exposures.
Plasma fluorescent oxidation products and short-term occupational particulate exposures.
复制标题
等离子体荧光氧化产物和短期职业颗粒物暴露。
DOI：
10.1002/ajim.22073
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发表时间：
2012
影响因子：
3.5
通讯作者：
Garshick,Eric
中科院分区：
文献类型：
--
作者：
Hart,JaimeE;Wu,Tianying;Laden,Francine;Garshick,Eric
BackgroundEvidence suggests that fine particulate air pollution results in oxidative induced tissue damage.MethodsA global fluorescent oxidation products (FLOx) assay (fluorescent intensity (FI) units per milliliter of plasma) was measured in blood samples collected from 236 nonsmoking, Caucasian, male trucking industry workers either prior to, during, or after their work shifts. Occupational exposures to particulate matter (PM)2.5were based on job‐specific area‐level sampling. Generalized linear models were used to determine associations between FLOx levels and PM2.5, adjusted for age, time since last meal, alcohol consumption, aspirin, and cholesterol medications.ResultsThe mean (standard deviation) level of FLOx was 265.9 FI/ml (96.0). Levels of FLOx were higher among older individuals and lower among those who had consumed alcohol in the past 24 hr. However, no associations were observed between FLOx and PM2.5.ConclusionsOur results indicate no association between occupational PM2.5exposure and this marker of global oxidative stress. Am. J. Ind. Med. 55:953–960, 2012. © 2012 Wiley Periodicals, Inc.
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