Epidemiology of type 1 diabetes.

Epidemiology of type 1 diabetes.
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DOI:
10.1016/j.ecl.2010.05.011
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发表时间:
2010-09
影响因子:
4.5
通讯作者:
Mayer-Davis, Elizabeth J.
Mayer-Davis, Elizabeth J.
中科院分区:
医学2区
文献类型:
--
作者:
Maahs, David M.;West, Nancy A.;Lawrence, Jean M.;Mayer-Davis, Elizabeth J.

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本章介绍了 1 型糖尿病 (T1D) 在世界各地和整个生命周期的流行病学。提出了按人口、地理、生物、文化和其他因素划分的 T1D 流行病学模式,以深入了解 T1D 的病因、自然史、风险和并发症。全球大型流行病学研究的数据表明,全球 1 型糖尿病的发病率已增加 2-5%,而在美国,到 18 岁,1 型糖尿病的患病率约为三百分之一。 T1D 风险因素研究是一个活跃的研究领域,旨在确定可能成为干预目标的遗传和环境触发因素。虽然 T1D 的临床护理取得了重大进展,生活质量和临床结果得到改善,但仍需要做更多工作来改善 T1D 的护理并最终找到治愈方法。流行病学研究对于调查 T1D 的复杂原因、临床护理、预防和治疗具有重要的持续作用。
This chapter describes the epidemiology of type 1 diabetes mellitus (T1D) around the world and across the lifespan. Epidemiologic patterns of T1D by demographic, geographic, biologic, cultural and other factors in populations are presented to gain insight about the etiology, natural history, risks, and complications of T1D. Data from large epidemiologic studies worldwide indicate that the incidence of T1D has been increasing by 2–5% worldwide and that the prevalence of T1D is approximately 1 in 300 in the US by 18 years of age. Research on risk factors for T1D is an active area of research to identify genetic and environmental triggers that could potentially be targeted for intervention. While significant advances have been made in the clinical care of T1D with resultant improvements in quality of life and clinical outcomes, much more needs to be done to improve care of, and ultimately find a cure for T1D. Epidemiologic studies have an important on-going role to investigate the complex causes, clinical care, prevention, and cure of T1D.
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