SilkDB: a knowledgebase for silkworm biology and genomics.
SilkDB: a knowledgebase for silkworm biology and genomics.
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DOI：
10.1093/nar/gki116
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Yu J
中科院分区：
文献类型：
--
作者：
Wang J;Xia Q;He X;Dai M;Ruan J;Chen J;Yu G;Yuan H;Hu Y;Li R;Feng T;Ye C;Lu C;Wang J;Li S;Wong GK;Yang H;Wang J;Xiang Z;Zhou Z;Yu J
家蚕知识库（SilkDB）是一个基于网络的家蚕遗传和基因组数据库，用于管理、整合和研究。随着家蚕基因组序列草图的完成，SilkDB提供了大规模全基因组序列组装、cDNA、表达序列标签（EST）簇、转座因子（TE）、突变体、单核苷酸多态性（SNP）和基因功能注释的集成表示，并将其分配到InterPro结构域和基因本体（GO）术语。SilkDB还包含一组来自家蚕（B.mori的野生祖先）的EST，以及一组来自其他鳞翅目昆虫的基因。以B.mori基因组序列为参考框架，展示了家蚕与野蚕、B. mori与其他鳞翅目昆虫、B.mori与两种已测序昆虫果蝇和蚊子的比较分析结果。SilkDB作为一个基础平台，致力于提供关于家蚕的全面知识库，并以系统和图形化的方式呈现家蚕基因组和相关信息，以便于深入的比较研究。SilkDB可在http://silkworm.genomics.org.cn上公开访问。
The Silkworm Knowledgebase (SilkDB) is a web-based repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a ∼6X draft genome sequence of the domestic silkworm (Bombyx mori), SilkDB provides an integrated representation of the large-scale, genome-wide sequence assembly, cDNAs, clusters of expressed sequence tags (ESTs), transposable elements (TEs), mutants, single nucleotide polymorphisms (SNPs) and functional annotations of genes with assignments to InterPro domains and Gene Ontology (GO) terms. SilkDB also hosts a set of ESTs from Bombyx mandarina, a wild progenitor of B.mori, and a collection of genes from other Lepidoptera. Comparative analysis results between the domestic and wild silkworm, between B.mori and other Lepidoptera, and between B.mori and the two sequenced insects, fruitfly and mosquito, are displayed by using B.mori genome sequence as a reference framework. Designed as a basic platform, SilkDB strives to provide a comprehensive knowledgebase about the silkworm and present the silkworm genome and related information in systematic and graphical ways for the convenience of in-depth comparative studies. SilkDB is publicly accessible at http://silkworm.genomics.org.cn.
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影响因子：
12.3
作者：
Celniker SE;Wheeler DA;Kronmiller B;Carlson JW;Halpern A;Patel S;Adams M;Champe M;Dugan SP;Frise E;Hodgson A;George RA;Hoskins RA;Laverty T;Muzny DM;Nelson CR;Pacleb JM;Park S;Pfeiffer BD;Richards S;Sodergren EJ;Svirskas R;Tabor PE;Wan K;Stapleton M;Sutton GG;Venter C;Weinstock G;Scherer SE;Myers EW;Gibbs RA;Rubin GM
通讯作者：
Rubin GM
影响因子：
12.3
作者：
通讯作者：
--
影响因子：
14.9
作者：
Harris, MA;Clark, J;White, R
通讯作者：
White, R
影响因子：
14.9
作者：
Mulder, NJ;Apweiler, R;Zdobnov, EM
通讯作者：
Zdobnov, EM
影响因子：
14.9
作者：
Benson, DA;Karsch-Mizrachi, I;Wheeler, DL
通讯作者：
Wheeler, DL