Treponema denticola and Porphyromonas gingivalis as prognostic markers following periodontal treatment.

Treponema denticola and Porphyromonas gingivalis as prognostic markers following periodontal treatment.
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齿垢密螺旋体和牙龈卟啉单胞菌作为牙周治疗后的预后标志物。

DOI:
10.1902/jop.1992.63.4.270
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发表时间:
1992
影响因子:
4.3
通讯作者:
Harold E. Morton
Harold E. Morton
中科院分区:
医学2区
文献类型:
--
作者:
Lloyd G. Simonson;Peter J. Robinson;Rory J. Pranger;M. Cohen;Harold E. Morton

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龈下菌斑样本收集前和3至11周后,洁治和根面平整牙周治疗的晚期牙周炎的个人。牙密螺旋体和牙龈卟啉单胞菌抗原的菌斑水平进行了测量治疗前和治疗后的定量免疫测定程序,使用这些口腔细菌的特异性单克隆抗体。T.牙周治疗后观察到牙垢(P <0.05)和牙龈卟啉单胞菌抗原(P <0.09)。健康状况的改善,通过探测深度的减少来衡量,与T的减少有关。齿垢抗原(P <0.05)。这些结果表明T.成功治疗部位的牙垢水平降低,而无反应部位的该微生物标记物水平等于或大于治疗前水平。这些结果为T.齿垢与成人严重牙周病相关,可作为疾病复发的预后标志。
Subgingival plaque samples were collected from individuals with advanced periodontitis before and 3 to 11 weeks after scaling and root planing periodontal treatment. The plaque levels of Treponema denticola and Porphyromonas gingivalis antigens were measured before and after treatment by a quantitative immunoassay procedure using monoclonal antibodies specific for these oral bacteria. A decrease in mean levels of T. denticola (P less than .05) and P. gingivalis antigens (P less than .09) were observed following periodontal therapy. Improved health, as measured by a decrease in probing depth, was associated with a decrease in T. denticola antigen (P less than .05). These results suggest that the T. denticola levels of successfully treated sites decreased, while non-responding sites had levels of this microbial marker which were equal to or greater than the pre-treatment levels. These results provide additional evidence that T. denticola is associated with human adult severe periodontal disease, and can serve as a prognostic marker for disease recurrence.
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发表时间: 1985
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