The achievement of comprehensive control targets among type 2 diabetes mellitus patients of different ages

The achievement of comprehensive control targets among type 2 diabetes mellitus patients of different ages
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不同年龄2型糖尿病患者综合控制目标完成情况

DOI:
10.18632/aging.103358
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发表时间:
2020-07
期刊:
影响因子:
5.2
通讯作者:
Tang Wei
Tang Wei
中科院分区:
医学2区
文献类型:
--
作者:
Yu Yun;Xie Kaipeng;Lou Qinglin;Xia Hui;Wu Dan;Dai Lingli;Hu Cuining;Wang Kunlin;Shan Shan;Hu Yun;Tang Wei

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目的:评价不同年龄组2型糖尿病(T2DM)患者综合控制的效果。结果:老年患者BMI(44.36%)、TC(50.83%)、LDL-C(48.27%)控制率均高于60 ~ 80岁患者和年轻患者(P <0.05)。多元logistic回归分析显示,老年患者比年轻患者更容易达到HbA1c(奇数比(OR) = 2.19)、TC (OR = 1.32)、HDL-C (OR = 1.35)和TG (OR = 1.74)的控制目标。这种影响在男性中更强(ORHbA1c = 2.27; ORTC = 1.41; ORHDL-C = 1.51; ORTG = 1.80)。相比之下,老年女性仅更有可能达到HbA1c < 7.0% (OR=1.88)。结论:综合防治策略仍需加强。方法:选取3126例T2DM患者,检测血压(BP)、体重指数(BMI)、糖化血红蛋白(HbA1c)、空腹血糖(FPG)、餐后血糖(PPG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)。我们将患者分为三个年龄组(<60岁、60-80岁和≥80岁),以评估在实现控制目标方面的差异。
Objective: To evaluate achievement of comprehensive controls among patients with type 2 diabetes mellitus (T2DM) in different age groups. Results: The elderly patients had higher control rates for BMI (44.36%), TC (50.83%) and LDL-C (48.27%) than those aged 60-80 years and younger patients (all P <0.05). Multiple logistic regression revealed that elderly patients were more likely to achieve control targets for HbA1c (odd ratio (OR) = 2.19), TC (OR = 1.32), HDL-C (OR = 1.35), and TG (OR = 1.74) than younger patients. This effect was stronger in males (ORHbA1c = 2.27; ORTC = 1.41; ORHDL-C = 1.51; ORTG = 1.80). By contrast, elderly females were only more likely to achieve HbA1c < 7.0% (OR=1.88). Conclusions: Our findings suggest that comprehensive control strategies still should be strengthened. Methods: A total of 3126 T2DM patients were included, and detected blood pressure (BP), body mass index (BMI), glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). We divided patients into three age groups (<60, 60-80 and ≥ 80 years), to assess the differences in achieving the control targets.
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发表时间: 2007-05
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影响因子: --
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