Associations between symptoms of pain, insomnia and depression, and frailty in older adults: A cross-sectional analysis of a cohort study.
Associations between symptoms of pain, insomnia and depression, and frailty in older adults: A cross-sectional analysis of a cohort study.
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疼痛、失眠、抑郁症状与老年人虚弱之间的关联：一项队列研究的横断面分析
DOI：
10.1016/j.ijnurstu.2021.103873
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发表时间：
2021-05
影响因子：
8.1
通讯作者：
Szanton, Sarah L.
中科院分区：
文献类型：
--
作者：
Liu, Minhui;Hou, Tianxue;Nkimbeng, Manka;Li, Yuxiao;Taylor, Janiece L.;Sun, Xiaocao;Tang, Siyuan;Szanton, Sarah L.
虚弱在老年人中普遍存在，并对多种健康结果产生不利影响。疼痛、失眠和抑郁症状是老年人常见且可治疗的症状，并且与虚弱有关。然而，尚不清楚这些症状是否与虚弱独立相关，以及它们如何相互作用，对虚弱产生比单个症状更大的影响。了解这些关联对于护士为体弱的老年人提供高质量的以患者为中心的护理非常重要。确定疼痛、失眠和抑郁症状与虚弱的独立关联，并检查它们对老年人虚弱的协同影响。队列研究的横断面分析。美国的社区。来自国家健康和老龄化趋势研究 (N = 7,609) 的社区居住老年人，这是一项针对美国医疗保险受益人的全国代表性调查。虚弱状态由身体虚弱表型的五个标准来确定：疲惫、体力活动少、虚弱、缓慢和萎缩。疼痛是根据上个月自我报告的令人烦恼的疼痛来确定的。失眠包括自我报告入睡困难和维持睡眠困难。抑郁症状通过患者健康问卷 2 进行评估。使用逻辑回归模型来调整社会人口统计、健康相关和行为协变量。样本主要为80岁以下（72%）、女性（57%）和非西班牙裔白人（81%）。大约53%的人经历过令人烦恼的疼痛，11%的人难以入睡，6%的人难以维持睡眠，15%的人有抑郁症状； 46% 处于虚弱状态，14% 处于虚弱状态。疼痛（比值比 [OR]：1.81，95% CI：1.60，2.04）、入睡困难（OR：1.23，95% CI：1.04，1.46）和抑郁症状（OR：2.29，95% CI：1.85，2.84）与虚弱前和虚弱存在独立关联。疼痛与抑郁症状之间的交互项（OR：1.87，95% CI：1.14，3.07）以及入睡困难与抑郁症状之间的交互项（OR：2.66，95% CI：1.15，6.13）显着，表明对虚弱前和虚弱具有协同影响。疼痛、入睡困难和抑郁症状是衰弱的独立危险因素，并且可能对衰弱产生协同影响。应制定干预措施来解决这些症状，以减少虚弱的不利影响。
Frailty is prevalent in older adults and has adverse effects on multiple health outcomes. Pain, insomnia, and depressive symptoms are commonly seen and treatable symptoms in older adults and are associated with frailty. However, it is unknown whether these symptoms are independently associated with frailty and how they interact with each other creating a greater impact on frailty than individual symptoms. It is important to understand these associations for nurses to provide high-quality patient-centered care for older adults with frailty. To determine independent associations of pain, insomnia, and depressive symptoms with frailty and examine their synergistic impact on frailty among older adults. A cross-sectional analysis of a cohort study. Communities in the United States. Community-dwelling older adults from the National Health and Aging Trend Study (N = 7,609), a nationally representative survey of Medicare Beneficiaries in the United States. Frailty status was determined by five criteria of the Physical Frailty Phenotype: exhaustion, low physical activity, weakness, slowness, and shrinking. Pain was determined by self-reports of bothersome pain in the last month. Insomnia included self-reports of difficulty initiating sleep and difficulty maintaining sleep. Depressive symptom was assessed by the Patient Health Questionnaire-2. Logistic regression models were used adjusting for sociodemographic, health-related and behavioral covariates. The sample was mainly under 80 years old (72%), female (57%), and non-Hispanic White (81%). Approximately 53% experienced bothersome pain, 11% had difficulty initiating sleep, 6% had difficulty maintaining sleep, and 15% had depressive symptom; 46% were pre-frail and 14% were frail. Independent associations with pre-frailty and frailty were found in pain (odds ratio [OR]: 1.81, 95% CI: 1.60, 2.04), difficulty initiating sleep (OR: 1.23, 95% CI: 1.04, 1.46) and depressive symptom (OR: 2.29, 95% CI: 1.85, 2.84). Interaction terms between pain and depressive symptom (OR: 1.87, 95% CI: 1.14, 3.07), and between difficulty initiating sleep and depressive symptom (OR: 2.66, 95% CI: 1.15, 6.13) were significant, suggesting a synergistic impact on pre-frailty and frailty. Pain, difficulty initiating sleep, and depressive symptoms are independent risk factors of frailty and may have a synergistic impact on frailty. Interventions should be developed to address these symptoms to reduce the adverse effects of frailty.
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DOI：
10.1111/j.1748-3743.2012.00312.x
发表时间：
2012-06-01
影响因子：
2.2
作者：
Finnbakk, Elisabeth;Skovdahl, Kirsti;Fagerstrom, Lisbeth
通讯作者：
Fagerstrom, Lisbeth
影响因子：
64.3
作者：
Blanken, Tessa F.;Benjamins, Jeroen S.;Van Someren, Eus J. W.
通讯作者：
Van Someren, Eus J. W.
影响因子：
6.3
作者：
Ensrud KE;Blackwell TL;Redline S;Ancoli-Israel S;Paudel ML;Cawthon PM;Dam TT;Barrett-Connor E;Leung PC;Stone KL;Osteoporotic Fractures in Men Study Group
通讯作者：
Osteoporotic Fractures in Men Study Group
影响因子：
7.2
作者：
Brown, Patrick J.;Roose, Steven P.;Rutherford, Bret R.
通讯作者：
Rutherford, Bret R.
影响因子：
3
作者：
Kroenke, K;Spitzer, RL;Williams, JBW
通讯作者：
Williams, JBW