Viral Diversity, Prey Preference, and Bartonella Prevalence in Desmodus rotundus in Guatemala.
Viral Diversity, Prey Preference, and Bartonella Prevalence in Desmodus rotundus in Guatemala.
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DOI：
10.1007/s10393-016-1183-z
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发表时间：
2016-12
期刊：
影响因子：
2.5
通讯作者：
Anthony, Simon J.
中科院分区：
文献类型：
--
作者：
Wray, Amy K.;Olival, Kevin J.;Moran, David;Renee Lopez, Maria;Alvarez, Danilo;Navarrete-Macias, Isamara;Liang, Eliza;Simmons, Nancy B.;Lipkin, W. Ian;Daszak, Peter;Anthony, Simon J.
关键词：
某些蝙蝠物种是几个主要病毒科的病原体的天然储存库，包括海尼帕病毒、丽莎病毒、冠状病毒和丝状病毒，这些病毒可能对人类健康构成严重威胁。普通吸血蝙蝠(Desmodus Rotundus)由于其数量丰富、涉及人和家畜的嗜血摄食习性以及高度的社会行为生态学，可能具有异常高的跨物种疾病传播潜力。以前的研究已经调查了圆锥形吸虫中狂犬病的动态，然而这些蝙蝠可能携带的其他病毒、细菌和其他微生物的多样性在很大程度上仍不清楚。我们对危地马拉捕获的13个病毒科和属的396份血液、尿液、唾液和粪便样本进行了筛选。横纹肌样病毒、腺病毒和疱疹病毒检测呈阳性结果。我们还对这些样本进行了巴尔通体的筛选。并发现38%的人检测呈阳性。为了表征与摄食行为相关的物种间传播的可能性，我们还分析了粪便样本中的细胞色素B序列，以识别猎物物种，并发现家牛(Bos Taurus)构成了血粉的大部分。我们的发现表明，包括在家养动物物种之间的病原体溢出的风险是可能的，需要进行进一步的研究来表征这种微生物多样性，并扩大我们对它们种群中觅食生态的理解。本文的在线版本(doi：10.1007/s10393-0161183-z)包含补充材料，授权用户可以使用。
Certain bat species serve as natural reservoirs for pathogens in several key viral families including henipa-, lyssa-, corona-, and filoviruses, which may pose serious threats to human health. The Common Vampire Bat (Desmodus rotundus), due to its abundance, sanguivorous feeding habit involving humans and domestic animals, and highly social behavioral ecology, may have an unusually high potential for interspecies disease transmission. Previous studies have investigated rabies dynamics in D. rotundus, yet the diversity of other viruses, bacteria, and other microbes that these bats may carry remains largely unknown. We screened 396 blood, urine, saliva, and fecal samples from D. rotundus captured in Guatemala for 13 viral families and genera. Positive results were found for rhabdovirus, adenovirus, and herpesvirus assays. We also screened these samples for Bartonella spp. and found that 38% of individuals tested positive. To characterize potential for interspecies transmission associated with feeding behavior, we also analyzed cytochrome B sequences from fecal samples to identify prey species and found that domestic cattle (Bos taurus) made up the majority of blood meals. Our findings suggest that the risk of pathogen spillover from Desmodus rotundus, including between domestic animal species, is possible and warrants further investigation to characterize this microbial diversity and expand our understanding of foraging ecology in their populations. The online version of this article (doi:10.1007/s10393-016-1183-z) contains supplementary material, which is available to authorized users.
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影响因子：
6.4
作者：
Anthony SJ;St Leger JA;Pugliares K;Ip HS;Chan JM;Carpenter ZW;Navarrete-Macias I;Sanchez-Leon M;Saliki JT;Pedersen J;Karesh W;Daszak P;Rabadan R;Rowles T;Lipkin WI
通讯作者：
Lipkin WI
影响因子：
11.8
作者：
Drexler JF;Corman VM;Wegner T;Tateno AF;Zerbinati RM;Gloza-Rausch F;Seebens A;Müller MA;Drosten C
通讯作者：
Drosten C
影响因子：
11.8
作者：
Bai Y;Kosoy M;Recuenco S;Alvarez D;Moran D;Turmelle A;Ellison J;Garcia DL;Estevez A;Lindblade K;Rupprecht C
通讯作者：
Rupprecht C
蝙蝠、食虫动物和啮齿动物携带的汉坦病毒的系统发育和起源
影响因子：
6.7
作者：
Guo WP;Lin XD;Wang W;Tian JH;Cong ML;Zhang HL;Wang MR;Zhou RH;Wang JB;Li MH;Xu J;Holmes EC;Zhang YZ
通讯作者：
Zhang YZ
影响因子：
11.8
作者：
da Rosa, Elizabeth S. T.;Kotait, Ivanete;Vasconcelos, Pedro F. C.
通讯作者：
Vasconcelos, Pedro F. C.