Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis - The Bunkyo Health Study.
Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis - The Bunkyo Health Study.
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前半月板挤压与膝关节骨关节炎中的胫骨前骨质宽度有关 - 邦基约健康研究。
DOI：
10.1016/j.ocarto.2023.100364
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发表时间：
2023-09
期刊：
影响因子：
--
通讯作者：
Ishijima, Muneaki
中科院分区：
文献类型：
--
作者：
Adili, Arepati;Kaneko, Haruka;Aoki, Takako;Liu, Lizu;Negishi, Yoshifumi;Tomura, Jun;Wakana, Suguru;Momoeda, Masahiro;Arita, Hitoshi;Hada, Shinnosuke;Shiozawa, Jun;Kubota, Mitsuaki;Someya, Yuki;Tamura, Yoshifumi;Aoki, Shigeki;Watada, Hirotaka;Kawamori, Ryuzo;Negishi-Koga, Takako;Okada, Yasunori;Ishijima, Muneaki
关键词：
在膝骨性关节炎(OA)中，内侧半月板同时向内侧和前方突出。我们报道了由软骨和骨部分组成的胫骨内侧骨赘的全长宽度与早期膝关节骨性关节炎的内侧半月板挤压直接相关，并假设胫骨前骨赘(ATO)也与前半月板挤压(AME)有关。因此，我们的目标是检查他们的患病率和关系。文乔健康研究队列中的老年受试者(638名女性和507名男性；平均年龄为72.9岁)被纳入其中。根据整体器官磁共振成像评分评价MRI检测到的骨性关节炎改变。采用质子密度加权脂肪抑制MRI伪彩色图像同时评价骨赘软骨和骨部分的方法评价ATO。大多数受试者膝关节内侧1/2膝关节Kellgren-Lawrence分级为OA(88.1%)、AME(94.3%，3.7±2.2mm)和ATO(99.6%，4.2±1.5mm)。在骨性关节炎的改变中，AME与ATO的全长宽度关系最为密切(多变量β和=0.877，p<；0.001)。受试者操作特征曲线下的面积为0.75(95%可信区间为0.60-0.84，p-<；0.001)。根据ATO宽度为2.9xmm来评估AME的存在的优势比为7.16(调整后为4.23-12.15，p<；0.001，年龄、性别、体重指数和K-L校正)。AME和ATO在老年人中是不可避免的，AME与ATO的全长宽度密切相关。我们的研究首次证明了AME与膝骨性关节炎患者ATO之间的密切关系。
In knee osteoarthritis (OA), medial meniscus extrudes both medially and anteriorly. We reported that full-length width of medial tibial osteophyte, which comprises cartilage and bone parts, is directly associated with medial meniscus extrusion in early-stage knee OA and hypothesized that anterior tibial osteophyte (ATO) is also associated with anterior meniscus extrusion (AME). Thus, we aimed to examine their prevalence and relationship. Elderly subjects (638 females and 507 males; average 72.9 years old) in the Bunkyo Health Study cohort were enrolled. MRI-detected OA changes were evaluated according to the Whole Organ Magnetic Resonance Imaging Score. ATO was evaluated using the method which can assess both cartilage and bone parts of osteophyte by pseudo-coloring images of proton density-weighted fat-suppressed MRI. Most subjects showed the Kellgren-Lawrence grade 1/2 of the medial knee OA (88.1%), AME (94.3%, 3.7 ± 2.2 mm), and ATO (99.6%, 4.2 ± 1.5 mm). Among the OA changes, AME was most closely associated with full-length width of ATO (multivariable β = 0.877, p < 0.001). The area under the receiver operating characteristic curve for determining the presence of AME as evaluated by ATO width was 0.75 (95% confidence interval 0.60–0.84, p < 0.001). The odds ratio for the presence of AME as evaluated by ATO width at 2.9 mm was 7.16 (4.23–12.15, p < 0.001, age, gender, BMI, and K-L adjusted). AME and ATO were inevitably observed in the elderly subjects and AME was closely associated with full-length width of ATO. Our study provides the first evidence on the close relationship between AME and ATO in knee OA.
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影响因子：
5.9
作者：
Miura Y;Ozeki N;Katano H;Aoki H;Okanouchi N;Tomita M;Masumoto J;Koga H;Sekiya I
通讯作者：
Sekiya I
影响因子：
27.4
作者：
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影响因子：
4.9
作者：
Hada S;Ishijima M;Kaneko H;Kinoshita M;Liu L;Sadatsuki R;Futami I;Yusup A;Takamura T;Arita H;Shiozawa J;Aoki T;Takazawa Y;Ikeda H;Aoki S;Kurosawa H;Okada Y;Kaneko K
通讯作者：
Kaneko K
影响因子：
4.9
作者：
Ding C;Martel-Pelletier J;Pelletier JP;Abram F;Raynauld JP;Cicuttini F;Jones G
通讯作者：
Jones G
DOI：
10.1016/j.ocarto.2022.100320
发表时间：
2022-12
期刊：
Osteoarthritis and cartilage open
影响因子：
--
作者：
Hada, Shinnosuke;Kaneko, Haruka;Liu, Lizu;Aoki, Takako;Takamura, Tomohiro;Kinoshita, Mayuko;Arita, Hitoshi;Shiozawa, Jun;Negishi, Yoshifumi;Momoeda, Masahiro;Kubota, Mitsuaki;Aoki, Shigeki;Okada, Yasunori;Ishijima, Muneaki
通讯作者：
Ishijima, Muneaki