Diarrheal morbidity during the first 2 years of life among HIV-infected infants
Diarrheal morbidity during the first 2 years of life among HIV-infected infants
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HIV 感染婴儿出生后 2 年内的腹泻发病率
DOI：
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
J. Clemens
中科院分区：
文献类型：
--
作者：
K. Kotloff;John P. Johnson;P. Nair;D. Hickman;P. Lippincott;P. Wilson;J. Clemens
Objective. —To determine the incidence, cause, and patterns of diarrhea during the first 2 years of life among infants infected perinatally with the human immunodeficiency virus (HIV). Design. —A cohort study in which infants were enrolled shortly after birth and followed up longitudinally using biweekly surveillance for the occurrence of diarrhea. Stool specimens collected at the onset of diarrhea were evaluated for enteropathogens. Infants who were infected with HIV were compared with uninfected infants. Subjects. —Infants born to HIV-infected women at the University of Maryland Hospital, Baltimore, were recruited at 0 to 3 months of age. This analysis included 58 infants enrolled in the cohort and followed up at least 15 months (unless death intervened) whose HIV status was established (18 HIV-infected infants and 40 HIV-uninfected infants). Measurements and Results. —The overall incidence of diarrhea in HIV-infected infants was 3.2 episodes per 12 child-months compared with 1.5 episodes per 12 child-months among HIV-uninfected infants (incidence density ratio, 2.2; P + T-lymphocyte counts by 1 year of age. Conclusions. —Both acute and persistent episodes of diarrhea are major sources of morbidity in HIV-infected infants. Moreover, persistent diarrhea is a marker for rapid progression of HIV disease. ( JAMA . 1994;271:448-452)
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影响因子：
7.1
作者：
KOTLER, DP;WANG, J;PIERSON, RN
通讯作者：
PIERSON, RN
患有和不患有获得性免疫缺陷综合症的同性恋男性肠道病原体的患病率。
影响因子：
29.4
作者：
Laughon,BE;Druckman,DA;Vernon,A;Quinn,TC;Polk,BF;Modlin,JF;Yolken,RH;Bartlett,JG
通讯作者：
Bartlett,JG
人类免疫缺陷病毒感染妇女所生婴儿的自然史和血清学诊断。
DOI：
10.1001/archpedi.1989.02150220037017
发表时间：
1989
期刊：
American journal of diseases of children (1960)
影响因子：
--
作者：
Johnson,JP;Nair,P;Hines,SE;Seiden,SW;Alger,L;Revie,DR;O'Neil,KM;Hebel,R
通讯作者：
Hebel,R
艾滋病肠病：慢性腹泻中的隐匿性肠道感染和十二指肠粘膜改变。
影响因子：
39.2
作者：
Greenson,JK;Belitsos,PC;Yardley,JH;Bartlett,JG
通讯作者：
Bartlett,JG