A transparent broadband ultrasonic detector based on an optical micro-ring resonator for photoacoustic microscopy.
A transparent broadband ultrasonic detector based on an optical micro-ring resonator for photoacoustic microscopy.
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DOI：
10.1038/srep04496
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发表时间：
2014-03-28
影响因子：
4.6
通讯作者：
Sun C
中科院分区：
文献类型：
--
作者：
Li H;Dong B;Zhang Z;Zhang HF;Sun C
光声显微镜(PAM)不依赖造影剂成像生物组织中的光吸收对比度。它特别适合于测量几个组织生理参数，如血红蛋白氧饱和度，否则这些参数仍然具有挑战性。研究人员正在围绕PAM设计新的临床诊断工具和多模式显微系统，以充分释放其潜力。然而，PAM中常用的尺寸较大且不透明的压电超声探测器对其造成了严重的限制。我们的解决方案是基于总厚度为250 μm的聚合物光学微环谐振器的盖滑式光学透明超声探测器，它能够在宽接收角度上实现高灵敏度的超声检测，带宽为140 Mhz，相当于光声饱和极限287 cm−1，估计噪声等效压力为6.8 Pa.我们还为PAM的MRR设计和优化建立了理论框架。
Photoacoustic microscopy (PAM) does not rely on contrast agent to image the optical absorption contrast in biological tissue. It is uniquely suited for measuring several tissue physiological parameters, such as hemoglobin oxygen saturation, that would otherwise remain challenging. Researchers are designing new clinical diagnostic tools and multimodal microscopic systems around PAM to fully unleash its potential. However, the sizeable and opaque piezoelectric ultrasonic detectors commonly used in PAM impose a serious constraint. Our solution is a coverslip-style optically transparent ultrasound detector based on a polymeric optical micro-ring resonator (MRR) with a total thickness of 250 μm. It enables highly-sensitive ultrasound detection over a wide receiving angle with a bandwidth of 140 MHz, which corresponds to a photoacoustic saturation limit of 287 cm−1, at an estimated noise-equivalent pressure (NEP) of 6.8 Pa. We also established a theoretical framework for designing and optimizing the MRR for PAM.
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影响因子：
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作者：
Gao, Liang;Zhang, Chi;Wang, Lihong V.
通讯作者：
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影响因子：
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