Drug-related stimuli impair inhibitory control in cocaine abusers.
Drug-related stimuli impair inhibitory control in cocaine abusers.
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DOI：
10.1016/j.drugalcdep.2013.08.004
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发表时间：
2013-12-01
影响因子：
4.2
通讯作者：
Rush CR
中科院分区：
文献类型：
--
作者：
Pike E;Stoops WW;Fillmore MT;Rush CR
Cocaine users show impaired inhibitory control on cued go/no-go tasks and attention bias to drug-related images in eye-tracking tasks. The results of a previous study suggested that there is a relationship between inhibitory control and attention bias in alcohol drinkers such that the presentation of alcohol-related images as a go cue in a cued go/no-go task significantly impaired inhibitory control compared to neutral images as a go cue. The present study determined the generality of these previous findings by assessing inhibitory control in cocaine users utilizing a modified cued go/no-go task with cocaine or neutral images as the cues. Non-treatment seeking cocaine users (N=30) completed the modified task after completing detailed measures of demographics and drug use. Participants were matched on basic demographic factors and were assigned to groups in which they saw either a cocaine or neutral image as the go cue. Participants assigned to the cocaine image go cue condition had a significantly higher proportion of inhibitory failures to the no-go target than their counterparts assigned to the neutral cue condition, but there were no group differences on reaction time (i.e., accuracy was not traded for speed). Cocaine users were less able to inhibit pre-potent responses when a cocaine-related image served as the go cue than when a neutral image served as the go cue, consistent with previous research in alcohol users. The outcomes suggest that cocaine-related cues produce disinhibition, perhaps contributing to the high incidence of relapse or continued cocaine use.
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DOI：
10.1177/1534582303257007
发表时间：
2003-09-01
期刊：
Behavioral and cognitive neuroscience reviews
影响因子：
--
作者：
Fillmore, Mark T
通讯作者：
Fillmore, Mark T
影响因子：
4.4
作者：
Verdejo-Garcia, Antonio J.;Perales, Jose C.;Perez-Garcia, Miguel
通讯作者：
Perez-Garcia, Miguel
影响因子：
2.9
作者：
Sevak RJ;Vansickel AR;Stoops WW;Glaser PE;Hays LR;Rush CR
通讯作者：
Rush CR
DOI：
10.3109/00952990.2010.543204
发表时间：
2011-03
期刊：
The American journal of drug and alcohol abuse
影响因子：
--
作者：
Liu S;Lane SD;Schmitz JM;Waters AJ;Cunningham KA;Moeller FG
通讯作者：
Moeller FG
影响因子：
3.4
作者：
Verdejo-Garcia, Antonio;Perez-Garcia, Miguel
通讯作者：
Perez-Garcia, Miguel