Tissue engineering of the penis.
Tissue engineering of the penis.
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DOI：
10.1100/2011/323989
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发表时间：
2011
影响因子：
--
通讯作者：
Atala A
中科院分区：
文献类型：
--
作者：
Patel MN;Atala A
泌尿生殖道的先天性疾病、癌症、创伤或其他病症可导致显著的器官损伤或功能丧失，最终需要重建或替换受损结构。然而，目前的重建技术受到组织可用性和相容性问题的限制。医生和科学家已经开始探索组织工程和再生医学策略，用于修复和重建泌尿生殖道。组织工程允许开发可能恢复正常功能的生物替代品。目前正在进行旨在治疗或替换大多数器官的组织工程努力。这些努力大多发生在过去十年中。然而，在这些工程技术应用于人类之前，还需要进一步的研究来确保这些新材料的安全性和有效性。最近的进展表明，工程泌尿组织和细胞治疗可能很快就有临床应用。
Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability.
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影响因子：
3.8
作者：
CAVALLARO, JF;KEMP, PD;KRAUS, KH
通讯作者：
KRAUS, KH
影响因子：
6.6
作者：
Atala, A;Guzman, L;Retik, AB
通讯作者：
Retik, AB
影响因子：
6.6
作者：
El Kassaby, AbdelWahab;AbouShwareb, Tamer;Atala, Anthony
通讯作者：
Atala, Anthony
影响因子：
6.6
作者：
Atala, A
通讯作者：
Atala, A
影响因子：
4.5
作者：
El-Assmy, A;El-Hamid, MA;Hafez, AT
通讯作者：
Hafez, AT