A comparative analysis of Y chromosome and mtDNA phylogenies of the Hylobates gibbons.
A comparative analysis of Y chromosome and mtDNA phylogenies of the Hylobates gibbons.
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DOI：
10.1186/1471-2148-12-150
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发表时间：
2012-08-21
影响因子：
3.4
通讯作者：
Vigilant L
中科院分区：
文献类型：
--
作者：
Chan YC;Roos C;Inoue-Murayama M;Inoue E;Shih CC;Vigilant L
近缘物种的进化关系一直是生物学家感兴趣的，因为这些物种在相对较短的时间内经历了不同的进化过程。通过比较线粒体、常染色体、X染色体和Y染色体等不同遗传模式的DNA序列，可以更全面地推断物种的进化历史。长臂猿，特别是长臂猿属，特别有趣，因为它们由多个密切相关的物种组成，这些物种迅速出现并生活在地理位置接近的地方。我们目前对长臂猿物种之间关系的理解主要是基于母系遗传的线粒体DNA（mtDNA）的数据。为了推断长臂猿类群的父系历史，我们对来自10个物种的26只长臂猿的多个Y染色体位点进行了测序。正如预期的那样，我们发现序列变异的水平比线粒体基因组（mtgenome）所观察到的低五倍。虽然我们的Y染色体系统发育树显示相对较低的分辨率相比，mtgenome树，我们的结果是一致的单系性的建议的mtgenome树的属。通过比较线粒体基因组和Y染色体数据的分歧分子年代和分歧树的分支模式，我们发现：1）Y染色体的分歧估计比线粒体基因组的分歧估计更近，2）物种H. larer和H. pileatus在线粒体基因组单系发生中分别为单系发生，而H. pileatus个体福尔斯归入H.最大Y染色体分支。基于本研究中26个个体的~6.4 kb的Y染色体DNA序列数据，我们提供了关于长臂猿特别是长臂猿进化的分子推断，与mtDNA数据互补。总的来说，我们的研究结果说明了效用的基因座与不同的遗传模式，调查潜在的性别特异性过程的进化历史上密切相关的类群的比较研究，并强调需要进一步采样的长臂猿的已知种源。
The evolutionary relationships of closely related species have long been of interest to biologists since these species experienced different evolutionary processes in a relatively short period of time. Comparison of phylogenies inferred from DNA sequences with differing inheritance patterns, such as mitochondrial, autosomal, and X and Y chromosomal loci, can provide more comprehensive inferences of the evolutionary histories of species. Gibbons, especially the genus Hylobates, are particularly intriguing as they consist of multiple closely related species which emerged rapidly and live in close geographic proximity. Our current understanding of relationships among Hylobates species is largely based on data from the maternally-inherited mitochondrial DNAs (mtDNAs). To infer the paternal histories of gibbon taxa, we sequenced multiple Y chromosomal loci from 26 gibbons representing 10 species. As expected, we find levels of sequence variation some five times lower than observed for the mitochondrial genome (mtgenome). Although our Y chromosome phylogenetic tree shows relatively low resolution compared to the mtgenome tree, our results are consistent with the monophyly of gibbon genera suggested by the mtgenome tree. In a comparison of the molecular dating of divergences and on the branching patterns of phylogeny trees between mtgenome and Y chromosome data, we found: 1) the inferred divergence estimates were more recent for the Y chromosome than for the mtgenome, 2) the species H. lar and H. pileatus are monophyletic in the mtgenome phylogeny, respectively, but a H. pileatus individual falls into the H. lar Y chromosome clade. Based on the ~6.4 kb of Y chromosomal DNA sequence data generated for each of the 26 individuals in this study, we provide molecular inferences on gibbon and particularly on Hylobates evolution complementary to those from mtDNA data. Overall, our results illustrate the utility of comparative studies of loci with different inheritance patterns for investigating potential sex specific processes on the evolutionary histories of closely related taxa, and emphasize the need for further sampling of gibbons of known provenance.
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