Muscle specification in the Xenopus laevis gastrula-stage embryo.
Muscle specification in the Xenopus laevis gastrula-stage embryo.
复制标题
非洲爪蟾原肠胚阶段胚胎的肌肉规格。
DOI:
10.1002/dvdy.20451
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发表时间:
2005
期刊:
影响因子:
--
通讯作者:
Domingo,CarmenR
中科院分区:
文献类型:
--
作者:
Wunderlich,Kathleen;Gustin,JeanK;Domingo,CarmenR
Recent fate maps of theXenopus laevisgastrula show that mesodermal tissue surrounding the blastopore gives rise to muscle (Keller [1991] Methods Cell Biol 36:61–113; Lane and Smith [1999] Development 126:423–434). In a significant deviation from earlier data, the new maps demonstrate that cells in the ventral half of the gastrula are precursors to a significant portion of trunk somites. However, these posterior somites are not formed until tadpole stages (stages 38–44). We therefore set out to determine the timing of muscle specification within the ventral half of the gastrula. Our approach was to generate a series of tissue explants from gastrula‐stage embryos and then culture them to either stage 28 (tailbud) or stage 44 (tadpole). At each endpoint, the presence of muscle in explants was assessed with a muscle‐specific antibody. Interestingly, we found that muscle tissue is detected in ventral explants. However, these explants must be cultured to the tadpole stage. This is perhaps not unexpected, as this is the point at which this tissue normally gives rise to muscle. We further show that muscle specification of the involuting marginal zone does not change over the course of gastrulation. Together, these results suggest that dorsalizing signals emanating from the midline during gastrulation are not necessary for muscle specification of the ventral half of the involuting marginal zone. Developmental Dynamics 233:1348–1358, 2005. © 2005 Wiley‐Liss, Inc.
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DOI:
10.1111/j.1432-0436.1985.tb00287.x
发表时间:
1985-03
期刊:
Differentiation; research in biological diversity
影响因子:
--
作者:
J. Maufroid;A. Capuron
通讯作者:
J. Maufroid;A. Capuron
DOI:
--
发表时间:
1985
期刊:
Journal of embryology and experimental morphology
影响因子:
--
作者:
P. Wigmore;N. Holder
通讯作者:
N. Holder
DOI:
10.2183/pjab1945.47.313
发表时间:
1971
期刊:
The Journal of Cell Biology
影响因子:
--
作者:
O. Nakamura;H. Takasaki;M. Ishihara
通讯作者:
M. Ishihara
影响因子:
2.7
作者:
A. Warner
通讯作者:
A. Warner
DOI:
10.1093/aesa/32.3.657
发表时间:
1938-10
期刊:
The Yale Journal of Biology and Medicine
影响因子:
--
作者:
Geo H Smith;R. R. Bensley-R.;L. Stone
通讯作者:
Geo H Smith;R. R. Bensley-R.;L. Stone