Personalized nanomedicine advancements for stem cell tracking.

Personalized nanomedicine advancements for stem cell tracking.
复制标题

DOI:
10.1016/j.addr.2012.07.008
复制
发表时间:
2012-10
影响因子:
16.1
通讯作者:
Walczak, Piotr
Walczak, Piotr
中科院分区:
医学1区
文献类型:
--
作者:
Janowski, Miroslaw;Bulte, Jeff W. M.;Walczak, Piotr

文献摘要

参考文献

被引文献

相似文献

生物医学的最新技术发展促进了个体患者在解剖学、生理学和分子水平上的数据的产生,从而为以前所未有的方式进行个性化治疗提供了机会。患者特定干细胞的产生体现了朝着这一新方法所做的努力。基于细胞的治疗是一种非常有前途的治疗模式;然而,由于缺乏关于干细胞在体内的命运的一致和公正的数据,对治疗的解释仍然具有挑战性,阻碍了这一领域的进展。具有广泛的无机和有机纳米结构的纳米技术的出现扩大了追踪移植干细胞的方法的武器库。纳米材料的多样性使个性化纳米医学发生了革命性的变化,并使干细胞标记材料能够针对每个患者的特定需求进行个性化定制。干细胞追踪的成功实施很可能是推动纳米他感生理学进一步发展的重要推动力。这篇综述的目的是强调使用目前可用的纳米颗粒进行细胞跟踪的作用。
Recent technological developments in biomedicine have facilitated the generation of data on the anatomical, physiological and molecular level for individual patients and thus introduces opportunity for therapy to be personalized in an unprecedented fashion. Generation of patient-specific stem cells exemplifies the efforts toward this new approach. Cell-based therapy is a highly promising treatment paradigm; however, due to the lack of consistent and unbiased data about the fate of stem cells in vivo, interpretation of therapeutic remains challenging hampering the progress in this field. The advent of nanotechnology with a wide palette of inorganic and organic nanostructures has expanded the arsenal of methods for tracking transplanted stem cells. The diversity of nanomaterials has revolutionized personalized nanomedicine and enables individualized tailoring of stem cell labeling materials for the specific needs of each patient. The successful implementation of stem cell tracking will likely be a significant driving force that will contribute to the further development of nanotheranostics. The purpose of this review is to emphasize the role of cell tracking using currently available nanoparticles.
DOI: 10.2147/ijn.s17995
发表时间: 2011
影响因子: 8
作者:
Bakalova R;Zhelev Z;Kokuryo D;Spasov L;Aoki I;Saga T
通讯作者: Saga T
DOI: 10.1002/mrm.21116
发表时间: 2007-01-01
影响因子: 3.3
作者:
Ben-Hur, Tamir;van Heeswijk, Ruud B.;Bulte, Jeff W. M.
通讯作者: Bulte, Jeff W. M.
DOI: 10.1073/pnas.152463399
发表时间: 2002-10-01
影响因子: 11.1
作者:
Åkerman, ME;Chan, WCW;Ruoslahti, E
通讯作者: Ruoslahti, E
DOI: 10.3389/fnene.2010.00021
发表时间: 2010-01-01
期刊: Frontiers in neuroenergetics
影响因子: --
作者:
Allegra Mascaro, Anna Letizia;Sacconi, Leonardo;Pavone, Francesco S
通讯作者: Pavone, Francesco S
DOI: 10.1148/radiol.11101608
发表时间: 2011-09-01
期刊: RADIOLOGY
影响因子: 19.7
作者:
Arifin, Dian R.;Long, Christopher M.;Bulte, Jeff W. M.
通讯作者: Bulte, Jeff W. M.