Cohort profile: the Women's Health Accelerometry Collaboration.
Cohort profile: the Women's Health Accelerometry Collaboration.
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DOI：
10.1136/bmjopen-2021-052038
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发表时间：
2021-11-29
期刊：
影响因子：
2.9
通讯作者：
LaCroix AZ
中科院分区：
文献类型：
--
作者：
Evenson KR;Bellettiere J;Cuthbertson CC;Di C;Dushkes R;Howard AG;Parada H Jr;Schumacher BT;Shiroma EJ;Wang G;Lee IM;LaCroix AZ
本文介绍了妇女的健康加速度合作，一个联盟的两个前瞻性队列研究的妇女年龄在62岁或以上，协调，以探讨加速度计评估的身体活动和久坐行为与癌症的发病率和死亡率的关联。共纳入23443名生活在美国并参与观察性研究的女性（平均年龄73.4岁，标准差6.8）; 17061名来自女性健康研究（WHS），6382名来自女性健康倡议客观身体活动和心血管健康（WHI/OPACH）研究。进行了加速度计、癌症结局和协变量协调，以使两项队列研究保持一致。在2011-2014年WHS和2012-2014年WHI/OPACH期间，使用ActiGraph GT 3X+加速度计在臀部佩戴1周，使用类似程序测量身体活动和久坐行为。通过使用医生裁定的癌症诊断进行持续监测来确定癌症结局。使用问卷调查或身体评估测量相关协变量。在23443名一天至少佩戴10小时加速计的女性中，22868名女性在7天中的≥4天至少佩戴10小时/天。分析样本（n=22 852）平均4976（SD 2669）步/天，平均从事80.8（SD 46.5）分钟/天的中度至剧烈，105.5（SD 33.3）分钟/天的轻度高和182.1（SD 46.1）分钟/天的轻度低体力活动。久坐行为的平均时间为8.7（SD 1.7）小时/天。总体而言，11.8%的队列在加速度计测量时患有癌症诊断（非黑色素瘤皮肤癌除外）。在平均5.9（SD 1.6）年的随访期间，发生了1378起癌症事件，其中414起是致命的。使用协调队列，我们将访问正在进行的癌症监测，以量化身体活动和久坐行为与癌症发病率和死亡率的关联。
This paper describes the Women’s Health Accelerometry Collaboration, a consortium of two prospective cohort studies of women age 62 years or older, harmonised to explore the association of accelerometer-assessed physical activity and sedentary behaviour with cancer incidence and mortality. A total of 23 443 women (age mean 73.4, SD 6.8) living in the USA and participating in an observational study were included; 17 061 from the Women’s Health Study (WHS) and 6382 from the Women’s Health Initiative Objective Physical Activity and Cardiovascular Health (WHI/OPACH) Study. Accelerometry, cancer outcomes and covariate harmonisation was conducted to align the two cohort studies. Physical activity and sedentary behaviour were measured using similar procedures with an ActiGraph GT3X+ accelerometer, worn at the hip for 1 week, during 2011–2014 for WHS and 2012–2014 for WHI/OPACH. Cancer outcomes were ascertained via ongoing surveillance using physician adjudicated cancer diagnosis. Relevant covariates were measured using questionnaire or physical assessments. Among 23 443 women who wore the accelerometer for at least 10 hours on a single day, 22 868 women wore the accelerometer at least 10 hours/day on ≥4 of 7 days. The analytical sample (n=22 852) averaged 4976 (SD 2669) steps/day and engaged in an average of 80.8 (SD 46.5) min/day of moderate-to-vigorous, 105.5 (SD 33.3) min/day of light high and 182.1 (SD 46.1) min/day of light low physical activity. A mean of 8.7 (SD 1.7) hours/day were spent in sedentary behaviour. Overall, 11.8% of the cohort had a cancer diagnosis (other than non-melanoma skin cancer) at the time of accelerometry measurement. During an average of 5.9 (SD 1.6) years of follow-up, 1378 cancer events among which 414 were fatal have occurred. Using the harmonised cohort, we will access ongoing cancer surveillance to quantify the associations of physical activity and sedentary behaviour with cancer incidence and mortality.
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影响因子：
37.8
作者：
Bellettiere, John;LaMonte, Michael J.;LaCroix, Andrea Z.
通讯作者：
LaCroix, Andrea Z.
影响因子：
6.3
作者：
LaMonte MJ;Buchner DM;Rillamas-Sun E;Di C;Evenson KR;Bellettiere J;Lewis CE;Lee IM;Tinker LF;Seguin R;Zaslovsky O;Eaton CB;Stefanick ML;LaCroix AZ
通讯作者：
LaCroix AZ
影响因子：
120.7
作者：
Cook, NR;Lee, IM;Buring, JE
通讯作者：
Buring, JE
影响因子：
4.5
作者：
LaCroix AZ;Rillamas-Sun E;Buchner D;Evenson KR;Di C;Lee IM;Marshall S;LaMonte MJ;Hunt J;Tinker LF;Stefanick M;Lewis CE;Bellettiere J;Herring AH
通讯作者：
Herring AH
DOI：
10.1123/jmpb.2020-0036
发表时间：
2021-03
期刊：
Journal for the measurement of physical behaviour
影响因子：
--
作者：
Bellettiere J;Tuz-Zahra F;Carlson JA;Ridgers ND;Liles S;Greenwood-Hickman MA;Walker RL;LaCroix AZ;Jankowska MM;Rosenberg DE;Natarajan L
通讯作者：
Natarajan L