Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing.
Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing.
复制标题
DOI：
10.1038/emi.2014.45
复制
发表时间：
2014-06
影响因子：
13.2
通讯作者：
Gottschalk, Marcelo
中科院分区：
文献类型：
--
作者：
Goyette-Desjardins, Guillaume;Auger, Jean-Philippe;Xu, Jianguo;Segura, Mariela;Gottschalk, Marcelo
猪链球菌是引起养猪业经济问题的重要病原体。此外，它是一种人畜共患病原体，可导致与受感染猪或猪衍生产品密切接触的人严重感染。虽然过去被认为是零星的，但人类S。在过去的45年中，已经报告了猪感染，在中国有两次大规模的暴发。事实上，近年来报告的人间病例数量大幅增加。在这篇综述中，我们介绍了猪（2002年至2013年）和人（1968年至2013年）的血清型和序列型（ST）的全球分布，这些血清型和序列型是通过多位点序列分型确定的。采用的方法对S.猪链球菌的鉴定和分型，目前流行病学知识的血清型和ST和人畜共患病的潜力。sui进行了讨论。提高对S的认识。在人类和兽医诊断实验室中的suis和进一步建立分型方法将有助于我们对这种病原体的了解，特别是在缺乏完整和/或最新数据的地区。还需要更多的研究来了解S. suis菌株，以及这些差异是否与特定血清型或ST相关。
Streptococcus suis is an important pathogen causing economic problems in the pig industry. Moreover, it is a zoonotic agent causing severe infections to people in close contact with infected pigs or pork-derived products. Although considered sporadic in the past, human S. suis infections have been reported during the last 45 years, with two large outbreaks recorded in China. In fact, the number of reported human cases has significantly increased in recent years. In this review, we present the worldwide distribution of serotypes and sequence types (STs), as determined by multilocus sequence typing, for pigs (between 2002 and 2013) and humans (between 1968 and 2013). The methods employed for S. suis identification and typing, the current epidemiological knowledge regarding serotypes and STs and the zoonotic potential of S. suis are discussed. Increased awareness of S. suis in both human and veterinary diagnostic laboratories and further establishment of typing methods will contribute to our knowledge of this pathogen, especially in regions where complete and/or recent data is lacking. More research is required to understand differences in virulence that occur among S. suis strains and if these differences can be associated with specific serotypes or STs.
登录
查看更多内容
影响因子：
2.1
作者：
Bonifait, Laetitia;Gottschalk, Marcelo;Grenier, Daniel
通讯作者：
Grenier, Daniel
影响因子：
--
作者：
BONMARCHAND, G;MASSARI, P;VANNIER, P
通讯作者：
VANNIER, P
影响因子：
5
作者：
AVRIL, MF;GHANASSIA, JP;MODAI, J
通讯作者：
MODAI, J
影响因子：
5
作者：
Bouchaud, L;Bourgain, C;Desechalliers, JP
通讯作者：
Desechalliers, JP
影响因子：
4.4
作者：
Brousseau, R;Hill, JE;Hemmingsen, SM
通讯作者：
Hemmingsen, SM