Added sugars mediate the relation between pre-pregnancy BMI and infant rapid weight gain: a preliminary study.
Added sugars mediate the relation between pre-pregnancy BMI and infant rapid weight gain: a preliminary study.
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DOI：
10.1038/s41366-021-00936-w
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发表时间：
2021-12
影响因子：
4.9
通讯作者：
Kong, Kai Ling
中科院分区：
文献类型：
--
作者：
Burgess, Brenda;Morris, Katherine S.;Faith, Myles S.;Paluch, Rocco A.;Kong, Kai Ling
父母肥胖与后代肥胖有关，尽管很少有研究探讨补充喂养期间可能影响这种关系的因素。本研究调查了婴儿添加糖的摄入量是否介导了母亲孕前体重指数（BMI）和婴儿快速体重增加（定义为年龄别体重百分位数交叉）之间的关系。本研究为横断面设计。获得了141对母婴的人体测量数据（平均年龄[标准差]：母亲32.6 [4.4]岁，婴儿11.9 [1.9]个月）。收集并分析了三次24小时召回的有关婴儿饮食的数据。皮尔森积差相关和多变量回归分析评估了孕前BMI、婴儿添加糖摄入量和年龄别体重百分比交叉之间的双变量关系。中介模型评估了添加糖和母乳喂养持续时间的影响。孕前BMI与婴儿的糖摄入量呈正相关（r = 0.230，p = 0.006）。添加糖的摄入量介导了孕前BMI对年龄别体重百分位交叉的影响（间接效应= 0.007，95% CI = 0.0001，0.0197，间接/总效应比= 0.280）。母乳喂养持续时间也调节了这种关系，母乳喂养持续时间较短的婴儿经历了更大的中介作用（间接效应= 0.010，95% CI = 0.0014，0.0277，间接/直接效应比= 0.7368）。怀孕前超重或肥胖的母亲更有可能给婴儿添加糖的食物和饮料，这种做法被发现可以调解母亲和婴儿肥胖之间的关系。母乳喂养持续时间调节添加糖在孕前BMI和婴儿体重快速增加之间的中介作用。
Parental obesity is linked to offspring obesity, though little research has explored factors that might influence this relationship during the complementary feeding period. This study investigated whether infant intakes of added sugars mediate the relationship between a mother’s pre-pregnancy body mass index (BMI) and infant rapid weight gain (defined as upward weight-for-age percentile crossing). This study was of a cross-sectional design. Anthropometrics for 141 mother-infant dyads (mean age [standard deviation]: 32.6 [4.4] year for mothers, 11.9 [1.9] months for infants) were obtained. Data from three 24-h recalls pertaining to the infants’ diets were collected and analyzed. Pearson product-moment correlations and multivariable regressions assessed bivariate relationships between pre-pregnancy BMI, infant added sugar intakes and upward weight-for-age percentile crossing. Mediation models evaluated the effects of added sugars and breastfeeding duration. Pre-pregnancy BMI correlated positively with infants’ added sugar intakes (r = 0.230, p = 0.006). Added sugar intakes mediated the impact of pre-pregnancy BMI on upward weight-for-age percentile crossing (indirect effect = 0.007, 95% CI = 0.0001, 0.0197, indirect/total effect ratio = 0.280). Breastfeeding duration also moderated the relationship, with infants who were breastfed for a shorter duration experiencing a greater mediating effect (indirect effect = 0.010, 95% CI = 0.0014, 0.0277, indirect/direct effect ratio = 0.7368). Mothers who were overweight or obese prior to pregnancy were significantly more likely to give their infants foods and beverages with added sugars, and this practice was found to mediate the relationship between maternal and infant obesity. Breastfeeding duration moderated the mediating effect of added sugars between pre-pregnancy BMI and infant rapid weight gain.
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作者：
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DOI：
10.1017/s2040174418001137
发表时间：
2019-10-01
影响因子：
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作者：
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