Exploring patterns enriched in a dataset with contrastive principal component analysis.
Exploring patterns enriched in a dataset with contrastive principal component analysis.
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DOI:
10.1038/s41467-018-04608-8
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发表时间:
2018-05-30
影响因子:
16.6
通讯作者:
Zou J
中科院分区:
文献类型:
--
作者:
Abid A;Zhang MJ;Bagaria VK;Zou J
Visualization and exploration of high-dimensional data is a ubiquitous challenge across disciplines. Widely used techniques such as principal component analysis (PCA) aim to identify dominant trends in one dataset. However, in many settings we have datasets collected under different conditions, e.g., a treatment and a control experiment, and we are interested in visualizing and exploring patterns that are specific to one dataset. This paper proposes a method, contrastive principal component analysis (cPCA), which identifies low-dimensional structures that are enriched in a dataset relative to comparison data. In a wide variety of experiments, we demonstrate that cPCA with a background dataset enables us to visualize dataset-specific patterns missed by PCA and other standard methods. We further provide a geometric interpretation of cPCA and strong mathematical guarantees. An implementation of cPCA is publicly available, and can be used for exploratory data analysis in many applications where PCA is currently used. Dimensionality reduction and visualization methods lack a principled way of comparing multiple datasets. Here, Abid et al. introduce contrastive PCA, which identifies low-dimensional structures enriched in one dataset compared to another and enables visualization of dataset-specific patterns.
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DOI:
10.3390/s16030323
发表时间:
2016-03-04
期刊:
Sensors (Basel, Switzerland)
影响因子:
--
作者:
Chen W;Ma H;Yu D;Zhang H
通讯作者:
Zhang H
影响因子:
3.7
作者:
Ahmed MM;Dhanasekaran AR;Block A;Tong S;Costa AC;Stasko M;Gardiner KJ
通讯作者:
Gardiner KJ
DOI:
10.1126/science.1251688
发表时间:
2014-06-13
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Moreno-Estrada A;Gignoux CR;Fernández-López JC;Zakharia F;Sikora M;Contreras AV;Acuña-Alonzo V;Sandoval K;Eng C;Romero-Hidalgo S;Ortiz-Tello P;Robles V;Kenny EE;Nuño-Arana I;Barquera-Lozano R;Macín-Pérez G;Granados-Arriola J;Huntsman S;Galanter JM;Via M;Ford JG;Chapela R;Rodriguez-Cintron W;Rodríguez-Santana JR;Romieu I;Sienra-Monge JJ;del Rio Navarro B;London SJ;Ruiz-Linares A;Garcia-Herrera R;Estrada K;Hidalgo-Miranda A;Jimenez-Sanchez G;Carnevale A;Soberón X;Canizales-Quinteros S;Rangel-Villalobos H;Silva-Zolezzi I;Burchard EG;Bustamante CD
通讯作者:
Bustamante CD
DOI:
10.1073/pnas.0903045106
发表时间:
2009-05-26
影响因子:
11.1
作者:
Silva-Zolezzi, Irma;Hidalgo-Miranda, Alfredo;Jimenez-Sanchez, Gerardo
通讯作者:
Jimenez-Sanchez, Gerardo
影响因子:
8
作者:
Barshan, Elnaz;Ghodsi, Ali;Jahromi, Mansoor Zolghadri
通讯作者:
Jahromi, Mansoor Zolghadri