Rapid coordination of effective learning by the human hippocampus.
Rapid coordination of effective learning by the human hippocampus.
复制标题
人类海马有效学习的快速协调。
DOI:
10.1126/sciadv.abf7144
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发表时间:
2021-06
期刊:
影响因子:
13.6
通讯作者:
Voss JL
中科院分区:
文献类型:
--
作者:
Kragel JE;Schuele S;VanHaerents S;Rosenow JM;Voss JL
Direct human brain recordings reveal how memory rapidly directs vision to support learning. Although the human hippocampus is necessary for long-term memory, controversial findings suggest that it may also support short-term memory in the service of guiding effective behaviors during learning. We tested the counterintuitive theory that the hippocampus contributes to long-term memory through remarkably short-term processing, as reflected in eye movements during scene encoding. While viewing scenes for the first time, short-term retrieval operative within the episode over only hundreds of milliseconds was indicated by a specific eye-movement pattern, which was effective in that it enhanced spatiotemporal memory formation. This viewing pattern was predicted by hippocampal theta oscillations recorded from depth electrodes and by shifts toward top-down influence of hippocampal theta on activity within visual perception and attention networks. The hippocampus thus supports short-term memory processing that coordinates behavior in the service of effective spatiotemporal learning.
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