Validity of predicting left ventricular end systolic pressure changes following an acute bout of exercise.

Validity of predicting left ventricular end systolic pressure changes following an acute bout of exercise.
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DOI:
10.1016/j.jsams.2012.05.003
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发表时间:
2013-01
影响因子:
4
通讯作者:
Fernhall B
Fernhall B
中科院分区:
医学2区
文献类型:
--
作者:
Kappus RM;Ranadive SM;Yan H;Lane AD;Cook MD;Hall G;Harvey IS;Wilund KR;Woods JA;Fernhall B

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左心室收缩末压 (LV ESP) 对于评估左心室性能很重要。 LV ESP 通常源自预测方程。目前尚不清楚这些方程对于年轻健康人群在休息时或运动后是否准确。我们比较了 60 名参与者在休息时、峰值有氧运动后 15 分钟和 30 分钟时测得的 LV ESP 与预测方程中的 LV ESP 值。 LV ESP 通过静息时、峰值循环运动后 15 分钟和 30 分钟后的压平眼压测量获得。与两个计算值相比,所有时间点测量的 LV ESP 均显着较低 (p<0.05)。在 15 年后和 30 后时间点,测得的 LV ESP 均较休息时显着下降 (p<0.05),并且与计算值相比变化不同(显着交互作用;p<0.05)。两个 LV ESP 方程也彼此显着不同 (p<0.05),并且随时间变化不同(显着交互作用;p<0.05)。这些数据表明,常用的两个预测方程不能准确预测年轻健康人群的静息或运动后 LV ESP。因此,年轻健康参与者的 LV ESP 需要单独确定。通过压平眼压计进行的非侵入性测量似乎可以更准确地确定 LV ESP。
Left ventricular end systolic pressure (LV ESP) is important in assessing left ventricular performance. LV ESP is usually derived from prediction equations. It is unknown whether these equations are accurate at rest or following exercise in a young, healthy population. We compared measured LV ESP versus LV ESP values from the prediction equations at rest, 15 minutes and 30 minutes following peak aerobic exercise in 60 participants. LV ESP was obtained by applanation tonometry at rest, 15 minutes post and 30 minutes post peak cycle exercise. Measured LV ESP was significantly lower (p<0.05) at all time points in comparison to the two calculated values. Measured LV ESP decreased significantly from rest at both the post15 and post30 time points (p<0.05) and changed differently in comparison to the calculated values (significant interaction; p<0.05). The two LV ESP equations were also significantly different from each other (p<0.05) and changed differently over time (significant interaction; p<0.05). These data indicate that the two prediction equations commonly used did not accurately predict either resting or post exercise LV ESP in a young, healthy population. Thus, LV ESP needs to be individually determined in young healthy participants. Non-invasive measurement through applanation tonometry appears to allow for a more accurate determination of LV ESP.
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